CD5 Antibody - #DF14431

(1)  
製品: CD5 Antibody
カタログ: DF14431
タンパク質の説明: Rabbit polyclonal antibody to CD5
アプリケーション: IF/ICC
反応性: Human, Mouse, Rat
分子量: 55kD(Calculated).
ユニプロット: P06127

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関連ダウンロード
MS Report
HPLC Report
MSDS
説明書
COA
プロトコル
WB Handbook
IHC Protocol
IF/ICC Protocol

製品説明

ソース:
Rabbit
アプリケーション:
IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse,Rat
クローナリティ:
Polyclonal
特異性:
CD5 Antibody detects endogenous levels of total CD5.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ／展開

CD 5; CD5; CD5 antigen (p56 62); CD5 antigen; CD5 molecule; CD5_HUMAN; LEU1; LyA; Lymphocyte antigen T1/Leu-1; OTTHUMP00000236973; T-cell surface glycoprotein CD5; T1;

免疫原

免疫原:

A synthesized peptide derived from Human CD5.

Uniprot:

P06127(CD5_HUMAN) >>Visit HPA database.

遺伝子(ID):
CD5(921)
タンパク質配列:
MPMGSLQPLATLYLLGMLVASCLGRLSWYDPDFQARLTRSNSKCQGQLEVYLKDGWHMVCSQSWGRSSKQWEDPSQASKVCQRLNCGVPLSLGPFLVTYTPQSSIICYGQLGSFSNCSHSRNDMCHSLGLTCLEPQKTTPPTTRPPPTTTPEPTAPPRLQLVAQSGGQHCAGVVEFYSGSLGGTISYEAQDKTQDLENFLCNNLQCGSFLKHLPETEAGRAQDPGEPREHQPLPIQWKIQNSSCTSLEHCFRKIKPQKSGRVLALLCSGFQPKVQSRLVGGSSICEGTVEVRQGAQWAALCDSSSARSSLRWEEVCREQQCGSVNSYRVLDAGDPTSRGLFCPHQKLSQCHELWERNSYCKKVFVTCQDPNPAGLAAGTVASIILALVLLVVLLVVCGPLAYKKLVKKFRQKKQRQWIGPTGMNQNMSFHRNHTATVRSHAENPTASHVDNEYSQPPRNSHLSAYPALEGALHRSSMQPDNSSDSDYDLHGAQRL

研究背景

機能:

May act as a receptor in regulating T-cell proliferation.

PTMs:

Phosphorylated on tyrosine residues by LYN; this creates binding sites for PTPN6/SHP-1.

細胞の位置付け:

Cell membrane>Single-pass type I membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
サブユニット構造:

Interacts with CD72/LYB-2. Interacts with PTPN6/SHP-1 (By similarity).

研究領域

· Organismal Systems > Immune system > Hematopoietic cell lineage.   (View pathway)

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