PAQR8 Antibody - #DF14563

(3)  
製品: PAQR8 Antibody
カタログ: DF14563
タンパク質の説明: Rabbit polyclonal antibody to PAQR8
アプリケーション: WB IHC IF/ICC
反応性: Human, Mouse
分子量: 40kD(Calculated).
ユニプロット: Q8TEZ7

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関連ダウンロード
MS Report
HPLC Report
MSDS
説明書
COA
プロトコル
WB Handbook
IHC Protocol
IF/ICC Protocol

製品説明

ソース:
Rabbit
アプリケーション:
IF/ICC 1:100-1:500, IHC 1:50-1:200, WB 1:500-1:2000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse
クローナリティ:
Polyclonal
特異性:
PAQR8 Antibody detects endogenous levels of PAQR8.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ／展開

C6orf33; LMPB1; Lysosomal membrane protein in brain 1; Membrane progestin receptor beta; mPR beta; MPRB; PAQR8; Progestin and adipoQ receptor family member 8; Progestin and adipoQ receptor family member VIII;

免疫原

免疫原:

A synthesized peptide derived from human PAQR8.

Uniprot:

Q8TEZ7(PAQR8_HUMAN) >>Visit HPA database.

遺伝子(ID):
PAQR8(85315)
発現特異性:
Q8TEZ7 PAQR8_HUMAN:

Highly expressed in the hypothalamus (PubMed:23161870). Also expressed in spinal cord, kidney and testis.

タンパク質配列:
MTTAILERLSTLSVSGQQLRRLPKILEDGLPKMPCTVPETDVPQLFREPYIRTGYRPTGHEWRYYFFSLFQKHNEVVNVWTHLLAALAVLLRFWAFAEAEALPWASTHSLPLLLFILSSITYLTCSLLAHLLQSKSELSHYTFYFVDYVGVSVYQYGSALAHFFYSSDQAWYDRFWLFFLPAAAFCGWLSCAGCCYAKYRYRRPYPVMRKICQVVPAGLAFILDISPVAHRVALCHLAGCQEQAAWYHTLQILFFLVSAYFFSCPVPEKYFPGSCDIVGHGHQIFHAFLSICTLSQLEAILLDYQGRQEIFLQRHGPLSVHMACLSFFFLAACSAATAALLRHKVKARLTKKDS

研究背景

機能:

Plasma membrane progesterone (P4) receptor coupled to G proteins. Seems to act through a G(i) mediated pathway. May be involved in oocyte maturation (By similarity). Also binds dehydroepiandrosterone (DHEA), pregnanolone, pregnenolone and allopregnanolone.

細胞の位置付け:

Cell membrane>Multi-pass membrane protein.
Note: Colocalizes with a lysosomal protein CTSD/cathepsin D.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Highly expressed in the hypothalamus. Also expressed in spinal cord, kidney and testis.

タンパク質ファミリー:

Belongs to the ADIPOR family.

Restrictive clause

 

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