PLA2G10 Antibody - #DF14565

(1)  
製品: PLA2G10 Antibody
カタログ: DF14565
タンパク質の説明: Rabbit polyclonal antibody to PLA2G10
アプリケーション: IF/ICC
反応性: Human, Mouse, Rat
分子量: 18kD(Calculated).
ユニプロット: O15496

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関連ダウンロード
MS Report
HPLC Report
MSDS
説明書
COA
プロトコル
WB Handbook
IHC Protocol
IF/ICC Protocol

製品説明

ソース:
Rabbit
アプリケーション:
IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse,Rat
クローナリティ:
Polyclonal
特異性:
PLA2G10 Antibody detects endogenous levels of PLA2G10.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ／展開

Group 10 secretory phospholipase A2; Group X secretory phospholipase A2; GX sPLA2; GXPLA2; GXSPLA2; PA2GX_HUMAN; Phosphatidylcholine 2 acylhydrolase GX; Phosphatidylcholine 2-acylhydrolase 10; Phospholipase A2 group X; PLA2G10; SPLA2; sPLA2-X; sPLA2X;

免疫原

免疫原:

A synthesized peptide derived from human PLA2G10.

Uniprot:

O15496(PA2GX_HUMAN) >>Visit HPA database.

遺伝子(ID):
PLA2G10(8399)
発現特異性:
O15496 PA2GX_HUMAN:

Found in spleen, thymus, peripheral blood leukocytes, pancreas, lung, and colon.

タンパク質配列:
MGPLPVCLPIMLLLLLPSLLLLLLLPGPGSGEASRILRVHRRGILELAGTVGCVGPRTPIAYMKYGCFCGLGGHGQPRDAIDWCCHGHDCCYTRAEEAGCSPKTERYSWQCVNQSVLCGPAENKCQELLCKCDQEIANCLAQTEYNLKYLFYPQFLCEPDSPKCD

研究背景

機能:

PA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides. Has a powerful potency for releasing arachidonic acid from cell membrane phospholipids. Prefers phosphatidylethanolamine and phosphatidylcholine liposomes to those of phosphatidylserine.

細胞の位置付け:

Secreted.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Found in spleen, thymus, peripheral blood leukocytes, pancreas, lung, and colon.

タンパク質ファミリー:

Belongs to the phospholipase A2 family.

研究領域

· Environmental Information Processing > Signal transduction > Ras signaling pathway.   (View pathway)

· Metabolism > Lipid metabolism > Glycerophospholipid metabolism.

· Metabolism > Lipid metabolism > Ether lipid metabolism.

· Metabolism > Lipid metabolism > Arachidonic acid metabolism.

· Metabolism > Lipid metabolism > Linoleic acid metabolism.

· Metabolism > Lipid metabolism > alpha-Linolenic acid metabolism.

· Metabolism > Global and overview maps > Metabolic pathways.

· Organismal Systems > Circulatory system > Vascular smooth muscle contraction.   (View pathway)

· Organismal Systems > Digestive system > Pancreatic secretion.

· Organismal Systems > Digestive system > Fat digestion and absorption.

Restrictive clause

 

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