CNPY3 Antibody - #DF14594
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
折りたたみ／展開
CAG repeat containing; CAG4A; Canopy 3 homolog; cnpy3; CNPY3_HUMAN; CTG repeat protein 4a; ERDA 5; ERDA5; Expanded repeat domain CAG/CTG 5; Expanded repeat-domain protein CAG/CTG 5; OTTHUMP00000016408; PRAT4A; Protein associated with Tlr4; Protein associated with Toll like receptor 4A; Protein canopy homolog 3; TNRC 5; Trinucleotide repeat containing 5; Trinucleotide repeat-containing gene 5 protein;
免疫原
A synthesized peptide derived from human CNPY3.
- Q9BT09 CNPY3_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MDSMPEPASRCLLLLPLLLLLLLLLPAPELGPSQAGAEENDWVRLPSKCEVCKYVAVELKSAFEETGKTKEVIGTGYGILDQKASGVKYTKSDLRLIEVTETICKRLLDYSLHKERTGSNRFAKGMSETFETLHNLVHKGVKVVMDIPYELWNETSAEVADLKKQCDVLVEEFEEVIEDWYRNHQEEDLTEFLCANHVLKGKDTSCLAEQWSGKKGDTAALGGKKSKKKSSRAKAAGGRSSSSKQRKELGGLEGDPSPEEDEGIQKASPLTHSPPDEL
研究背景
Toll-like receptor (TLR)-specific co-chaperone for HSP90B1. Required for proper TLR folding, except that of TLR3, and hence controls TLR exit from the endoplasmic reticulum. Consequently, required for both innate and adaptive immune responses (By similarity).
Endoplasmic reticulum.
Interacts with HSP90B1; this interaction is disrupted in the presence of ATP. Interacts with TLR1, TLR2, TLR4 and TLR9 (By similarity). Strongest interaction with TLR4 (By similarity).
Belongs to the canopy family.
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