NUP35 Antibody - #DF14683

(1)  
製品: NUP35 Antibody
カタログ: DF14683
タンパク質の説明: Rabbit polyclonal antibody to NUP35
アプリケーション: IHC
反応性: Human, Mouse, Rat
分子量: 35kD(Calculated).
ユニプロット: Q8NFH5

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MS Report
HPLC Report
MSDS
説明書
COA
プロトコル
WB Handbook
IHC Protocol
IF/ICC Protocol

製品説明

ソース:
Rabbit
アプリケーション:
IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse,Rat
クローナリティ:
Polyclonal
特異性:
NUP35 Antibody detects endogenous levels of NUP35.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ／展開

35 kDa nucleoporin; Mitotic phosphoprotein 44; MP 44; MP-44; NP 44; NP44; Nuclear pore complex protein 53kDa; Nuclear pore complex protein Nup 53; Nuclear pore complex protein Nup53; Nuclear pore protein NUP 53; Nuclear pore protein NUP53; Nucleoporin 35kDa; Nucleoporin 53kDa; Nucleoporin Nup 35; Nucleoporin NUP 53; Nucleoporin Nup35; Nucleoporin NUP53; NUP 35; Nup 53; NUP35; NUP53; NUP53_HUMAN;

免疫原

免疫原:

A synthesized peptide derived from human NUP35.

Uniprot:

Q8NFH5(NUP35_HUMAN) >>Visit HPA database.

遺伝子(ID):
NUP35(129401)
タンパク質配列:
MAAFAVEPQGPALGSEPMMLGSPTSPKPGVNAQFLPGFLMGDLPAPVTPQPRSISGPSVGVMEMRSPLLAGGSPPQPVVPAHKDKSGAPPVRSIYDDISSPGLGSTPLTSRRQPNISVMQSPLVGVTSTPGTGQSMFSPASIGQPRKTTLSPAQLDPFYTQGDSLTSEDHLDDSWVTVFGFPQASASYILLQFAQYGNILKHVMSNTGNWMHIRYQSKLQARKALSKDGRIFGESIMIGVKPCIDKSVMESSDRCALSSPSLAFTPPIKTLGTPTQPGSTPRISTMRPLATAYKASTSDYQVISDRQTPKKDESLVSKAMEYMFGW

研究背景

機能:

Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. May play a role in the association of MAD1 with the NPC.

細胞の位置付け:

Nucleus>Nuclear pore complex. Nucleus membrane>Peripheral membrane protein.
Note: Tightly associated with the nuclear membrane and lamina.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
サブユニット構造:

Interacts with TMEM48/NDC1. Forms a complex with NUP93, NUP155, NUP205 and lamin B; the interaction with NUP93 is direct.

タンパク質ファミリー:

Belongs to the Nup35 family.

研究領域

· Genetic Information Processing > Translation > RNA transport.

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