製品: PTOV1 Antibody
カタログ: DF14721
タンパク質の説明: Rabbit polyclonal antibody to PTOV1
アプリケーション: IHC
反応性: Human, Mouse
分子量: 47kD(Calculated).
ユニプロット: Q86YD1

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製品説明

ソース:
Rabbit
アプリケーション:
IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse
クローナリティ:
Polyclonal
特異性:
PTOV1 Antibody detects endogenous levels of PTOV1.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

ACID2; Activator interaction domain containing protein 2; Gcap3; prostate tumor overexpressed 1; Prostate tumor overexpressed gene 1; PTOV 1;

免疫原

免疫原:

A synthesized peptide derived from human PTOV1.

Uniprot:
遺伝子(ID):
発現特異性:
Q86YD1 PTOV1_HUMAN:

Expressed in brain, heart, kidney, liver, placenta, skeletal muscle and small intestine.

タンパク質配列:
MVRPRRAPYRSGAGGPLGGRGRPPRPLVVRAVRSRSWPASPRGPQPPRIRARSAPPMEGARVFGALGPIGPSSPGLTLGGLAVSEHRLSNKLLAWSGVLEWQEKRRPYSDSTAKLKRTLPCQAYVNQGENLETDQWPQKLIMQLIPQQLLTTLGPLFRNSQLAQFHFTNRDCDSLKGLCRIMGNGFAGCMLFPHISPCEVRVLMLLYSSKKKIFMGLIPYDQSGFVSAIRQVITTRKQAVGPGGVNSGPVQIVNNKFLAWSGVMEWQEPRPEPNSRSKRWLPSHVYVNQGEILRTEQWPRKLYMQLIPQQLLTTLVPLFRNSRLVQFHFTKDLETLKSLCRIMDNGFAGCVHFSYKASCEIRVLMLLYSSEKKIFIGLIPHDQGNFVNGIRRVIANQQQVLQRNLEQEQQQRGMGG

研究背景

機能:

May activate transcription. Required for nuclear translocation of FLOT1. Promotes cell proliferation.

細胞の位置付け:

Cell membrane. Cytoplasm>Perinuclear region. Nucleus.
Note: Translocates from the cytoplasm to the nucleus at the onset of S-phase. Also localizes to lipid rafts.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Expressed in brain, heart, kidney, liver, placenta, skeletal muscle and small intestine.

サブユニット構造:

May interact with CREBBP. Interacts with FLOT1.

タンパク質ファミリー:

Belongs to the Mediator complex subunit 25 family. PTOV1 subfamily.

Restrictive clause

 

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