製品: DERA Antibody
カタログ: DF14813
タンパク質の説明: Rabbit polyclonal antibody to DERA
アプリケーション: WB IHC
反応性: Human, Mouse
分子量: 35kD(Calculated).
ユニプロット: Q9Y315

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製品説明

ソース:
Rabbit
アプリケーション:
IHC 1:50-1:200, WB 1:500-1:2000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse
クローナリティ:
Polyclonal
特異性:
DERA Antibody detects endogenous levels of DERA.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

Deoxyriboaldolase; 2 deoxyribose 5 phosphate aldolase homolog C. elegans; CGI 26; CGI26; DEOC; DEOC_HUMAN; Deoxyriboaldolase; Deoxyribose phosphate aldolase like; DERA; Phosphodeoxyriboaldolase; Putative deoxyribose phosphate aldolase; Putative deoxyribose-phosphate aldolase;

免疫原

免疫原:

A synthesized peptide derived from human DERA.

Uniprot:
遺伝子(ID):
発現特異性:
Q9Y315 DEOC_HUMAN:

Mainly expressed in liver, lung and colon.

タンパク質配列:
MSAHNRGTELDLSWISKIQVNHPAVLRRAEQIQARRTVKKEWQAAWLLKAVTFIDLTTLSGDDTSSNIQRLCYKAKYPIREDLLKALNMHDKGITTAAVCVYPARVCDAVKALKAAGCNIPVASVAAGFPAGQTHLKTRLEEIRLAVEDGATEIDVVINRSLVLTGQWEALYDEIRQFRKACGEAHLKTILATGELGTLTNVYKASMIAMMAGSDFIKTSTGKETVNATFPVAIVMLRAIRDFFWKTGNKIGFKPAGGIRSAKDSLAWLSLVKEELGDEWLKPELFRIGASTLLSDIERQIYHHVTGRYAAYHDLPMS

研究背景

機能:

Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate. Participates in stress granule (SG) assembly. May allow ATP production from extracellular deoxyinosine in conditions of energy deprivation.

細胞の位置付け:

Cytoplasm. Cytoplasmic granule. Nucleus.
Note: Recruited to stress granules but not to processing bodies upon arsenite or clotrimazole treatment or energy deprivation.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Mainly expressed in liver, lung and colon.

サブユニット構造:

Interacts with YBX1.

タンパク質ファミリー:

Belongs to the DeoC/FbaB aldolase family. DeoC type 2 subfamily.

研究領域

· Metabolism > Carbohydrate metabolism > Pentose phosphate pathway.

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