VPS28 Antibody - #DF14882

製品: VPS28 Antibody
カタログ: DF14882
タンパク質の説明: Rabbit polyclonal antibody to VPS28
アプリケーション: ELISA(peptide)
反応性: Human, Mouse, Rat
分子量: 25kD(Calculated).
ユニプロット: Q9UK41

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MS Report
HPLC Report
MSDS
説明書
COA
プロトコル
WB Handbook
IHC Protocol
IF/ICC Protocol

製品説明

ソース:
Rabbit
アプリケーション:
ELISA(peptide) 1:20000-1:40000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse,Rat
クローナリティ:
Polyclonal
特異性:
VPS28 Antibody detects endogenous levels of VPS28.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ／展開

ESCRT-I complex subunit VPS28; H-Vps28; Vacuolar protein sorting 28; Vacuolar protein sorting 28 (yeast); Vacuolar protein sorting 28 homolog (S. cerevisiae); Vacuolar protein sorting 28 homolog; Vacuolar protein sorting-associated protein 28 homolog; VPS 28; Vps28; VPS28_HUMAN; Yeast class E protein Vps28p homolog;

免疫原

免疫原:

A synthesized peptide derived from human VPS28.

Uniprot:

Q9UK41(VPS28_HUMAN) >>Visit HPA database.

遺伝子(ID):
VPS28(51160)
タンパク質配列:
MFHGIPATPGIGAPGNKPELYEEVKLYKNAREREKYDNMAELFAVVKTMQALEKAYIKDCVSPSEYTAACSRLLVQYKAAFRQVQGSEISSIDEFCRKFRLDCPLAMERIKEDRPITIKDDKGNLNRCIADVVSLFITVMDKLRLEIRAMDEIQPDLRELMETMHRMSHLPPDFEGRQTVSQWLQTLSGMSASDELDDSQVRQMLFDLESAYNAFNRFLHA

研究背景

機能:

Component of the ESCRT-I complex, a regulator of vesicular trafficking process.

細胞の位置付け:

Cell membrane. Late endosome membrane>Peripheral membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
サブユニット構造:

Component of the ESCRT-I complex (endosomal sorting complex required for transport I) which consists of TSG101, VPS28, a VPS37 protein (VPS37A to -D) and MVB12A or MVB12B in a 1:1:1:1 stoichiometry. Interacts with TSG101, VPS37B, VPS37C, MVB12A and MVB12B. Component of an ESCRT-I complex (endosomal sorting complex required for transport I) which consists of TSG101, VPS28, VPS37A and UBAP1 in a 1:1:1:1 stoichiometry. Interacts WITH VPS36; the interaction mediates the association with the ESCRT-II complex. Interacts with SNF8 and VPS25. Interacts with CEP55.

タンパク質ファミリー:

Belongs to the VPS28 family.

研究領域

· Cellular Processes > Transport and catabolism > Endocytosis.   (View pathway)

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