Tubulin gamma Antibody - #AF0285
| 製品: | Tubulin gamma Antibody |
| カタログ: | AF0285 |
| タンパク質の説明: | Rabbit polyclonal antibody to Tubulin gamma |
| アプリケーション: | WB IHC |
| 反応性: | Human, Mouse, Rat |
| 予測: | Zebrafish |
| 分子量: | 51kDa; 51kD(Calculated). |
| ユニプロット: | P23258 |
| RRID: | AB_2833453 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# AF0285, RRID:AB_2833453.
折りたたみ／展開
Gamma 1 tubulin; Gamma 2 tubulin; Gamma Tubulin 1; Gamma Tubulin 2; Gamma tubulin complex component 1; Gamma-2-tubulin; GCP 1; GCP1; MGC131994; TBG2_HUMAN; TUBG; TUBG1; TUBG2; TUBGCP1; Tubulin gamma 1 chain; Tubulin gamma 2 chain; Tubulin gamma complex-associated protein 1; Tubulin gamma-2 chain; tubulin, gamma 1; tubulin, gamma 2; tubulin, gamma polypeptide; Xgam;
免疫原
A synthesized peptide derived from human Tubulin gamma, corresponding to a region within N-terminal amino acids.
- P23258 TBG1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MPREIITLQLGQCGNQIGFEFWKQLCAEHGISPEGIVEEFATEGTDRKDVFFYQADDEHYIPRAVLLDLEPRVIHSILNSPYAKLYNPENIYLSEHGGGAGNNWASGFSQGEKIHEDIFDIIDREADGSDSLEGFVLCHSIAGGTGSGLGSYLLERLNDRYPKKLVQTYSVFPNQDEMSDVVVQPYNSLLTLKRLTQNADCVVVLDNTALNRIATDRLHIQNPSFSQINQLVSTIMSASTTTLRYPGYMNNDLIGLIASLIPTPRLHFLMTGYTPLTTDQSVASVRKTTVLDVMRRLLQPKNVMVSTGRDRQTNHCYIAILNIIQGEVDPTQVHKSLQRIRERKLANFIPWGPASIQVALSRKSPYLPSAHRVSGLMMANHTSISSLFERTCRQYDKLRKREAFLEQFRKEDMFKDNFDEMDTSREIVQQLIDEYHAATRPDYISWGTQEQ
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P23258 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S32 | Phosphorylation | Uniprot | |
| K48 | Ubiquitination | Uniprot | |
| S80 | Phosphorylation | P24941 (CDK2) | Uniprot |
| K84 | Ubiquitination | Uniprot | |
| K113 | Ubiquitination | Uniprot | |
| S129 | Phosphorylation | Uniprot | |
| S131 | Phosphorylation | Q8TDC3-2 (BRSK1) | Uniprot |
| K164 | Ubiquitination | Uniprot | |
| K193 | Ubiquitination | Uniprot | |
| S284 | Phosphorylation | Uniprot | |
| K287 | Ubiquitination | Uniprot | |
| R295 | Methylation | Uniprot | |
| K301 | Ubiquitination | Uniprot | |
| S306 | Phosphorylation | Uniprot | |
| T307 | Phosphorylation | Uniprot | |
| K335 | Ubiquitination | Uniprot | |
| S336 | Phosphorylation | Uniprot | |
| K344 | Ubiquitination | Uniprot | |
| K363 | Ubiquitination | Uniprot | |
| S364 | Phosphorylation | Uniprot | |
| S385 | Phosphorylation | Q8TDC3 (BRSK1) | Uniprot |
| K397 | Acetylation | Uniprot | |
| K400 | Acetylation | Uniprot | |
| K400 | Ubiquitination | Uniprot | |
| K410 | Ubiquitination | Uniprot | |
| K415 | Ubiquitination | Uniprot | |
| T423 | Phosphorylation | Uniprot | |
| S424 | Phosphorylation | Uniprot |
研究背景
Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome. Pericentriolar matrix component that regulates alpha/beta chain minus-end nucleation, centrosome duplication and spindle formation.
Phosphorylation at Ser-131 by BRSK1 regulates centrosome duplication, possibly by mediating relocation of gamma-tubulin and its associated proteins from the cytoplasm to the centrosome.
Cytoplasm>Cytoskeleton>Microtubule organizing center>Centrosome.
Interacts with TUBGCP2 and TUBGCP3. Interacts with B9D2 (By similarity). Interacts with CDK5RAP2; the interaction is leading to centrosomal localization of TUBG1 and CDK5RAP2. Interacts with PIFO. Interacts with SAS6 and NUP62 at the centrosome.
Belongs to the tubulin family.
研究領域
· Human Diseases > Infectious diseases: Viral > Human papillomavirus infection.
Restrictive clause
Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.
For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.