GPX2 Antibody - #DF15267

(1)  
製品: GPX2 Antibody
カタログ: DF15267
タンパク質の説明: Rabbit polyclonal antibody to GPX2
アプリケーション: IF/ICC
反応性: Human, Mouse, Rat
分子量: 22kD(Calculated).
ユニプロット: P18283

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関連ダウンロード
MS Report
HPLC Report
MSDS
説明書
COA
プロトコル
WB Handbook
IHC Protocol
IF/ICC Protocol

製品説明

ソース:
Rabbit
アプリケーション:
IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse,Rat
クローナリティ:
Polyclonal
特異性:
GPX2 Antibody detects endogenous levels of GPX2.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ／展開

Gastrointestinal glutathione peroxidase; GI GPx; Glutathione peroxidase 2 (gastrointestinal); Glutathione peroxidase 2; Glutathione peroxidase gastrointestinal; Glutathione peroxidase related protein 2; Glutathione peroxidase-gastrointestinal; Glutathione peroxidase-related protein 2; GPRP; GPRP-2; GPx 2; GPx-2; GPx-GI; GPX2; GPX2_HUMAN; GSHPx 2; GSHPx GI; GSHPx-2; GSHPx-GI;

免疫原

免疫原:

A synthesized peptide derived from human GPX2.

Uniprot:

P18283(GPX2_HUMAN) >>Visit HPA database.

遺伝子(ID):
GPX2(2877)
発現特異性:
P18283 GPX2_HUMAN:

Mostly in liver and gastrointestinal tract, not found in heart or kidney.

タンパク質配列:
MAFIAKSFYDLSAISLDGEKVDFNTFRGRAVLIENVASLUGTTTRDFTQLNELQCRFPRRLVVLGFPCNQFGHQENCQNEEILNSLKYVRPGGGYQPTFTLVQKCEVNGQNEHPVFAYLKDKLPYPYDDPFSLMTDPKLIIWSPVRRSDVAWNFEKFLIGPEGEPFRRYSRTFPTINIEPDIKRLLKVAI

研究背景

機能:

Could play a major role in protecting mammals from the toxicity of ingested organic hydroperoxides. Tert-butyl hydroperoxide, cumene hydroperoxide and linoleic acid hydroperoxide but not phosphatidycholine hydroperoxide, can act as acceptors.

細胞の位置付け:

Cytoplasm.
Note: Mainly cytoplasmic.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Mostly in liver and gastrointestinal tract, not found in heart or kidney.

サブユニット構造:

Homotetramer.

タンパク質ファミリー:

Belongs to the glutathione peroxidase family.

研究領域

· Metabolism > Metabolism of other amino acids > Glutathione metabolism.

· Metabolism > Lipid metabolism > Arachidonic acid metabolism.

· Organismal Systems > Endocrine system > Thyroid hormone synthesis.

Restrictive clause

 

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