RPL23A Antibody - #DF15375
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
折りたたみ／展開
60S ribosomal protein L23A; FLJ27455; L23A; MDA20; Melanoma differentiation-associated gene 20; Ribosomal protein L23a; RL23A_HUMAN; RPL23A;
免疫原
A synthesized peptide derived from human RPL23A.
- P62750 RL23A_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAPKAKKEAPAPPKAEAKAKALKAKKAVLKGVHSHKKKKIRTSPTFRRPKTLRLRRQPKYPRKSAPRRNKLDHYAIIKFPLTTESAMKKIEDNNTLVFIVDVKANKHQIKQAVKKLYDIDVAKVNTLIRPDGEKKAYVRLAPDYDALDVANKIGII
研究背景
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. Binds a specific region on the 26S rRNA. May promote p53/TP53 degradation possibly through the stimulation of MDM2-mediated TP53 polyubiquitination.
N-terminus is methylated by METTL11A/NTM1.
Citrullinated by PADI4.
Interacts with LYAR and GNL2. Interacts with MDM2; this interaction may promote MDM2-mediated p53/TP53 polyubiquitination.
Belongs to the universal ribosomal protein uL23 family.
研究領域
· Genetic Information Processing > Translation > Ribosome.
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