RCAN3 Antibody - #DF15599
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
折りたたみ／展開
Calcipressin-3; Down syndrome candidate region 1 like 2; Down syndrome candidate region 1 like 2; regulator of calcineurin 3; Down syndrome candidate region 1 like protein 2; Down syndrome candidate region 1-like protein 2; Down syndrome critical region gene 1 like 2; DSCR1L2; hRCN3; MCIP3; Myocyte enriched calcineurin interacting protein 3; Myocyte-enriched calcineurin-interacting protein 3; RCAN family member 3; RCAN3; RCAN3_HUMAN; RCN3; Regulator of calcineurin 3; Regulator of calcineurin 3 isoform 1b,2;
免疫原
A synthesized peptide derived from human RCAN3.
Highest expression in heart, skeletal muscle kidney, liver and peripheral blood leukocytes. Lower expression in all other tissues.
- Q9UKA8 RCAN3_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MLRDTMKSWNDSQSDLCSTDQEEEEEMIFGENEDDLDEMMDLSDLPTSLFACSVHEAVFEAREQKERFEALFTIYDDQVTFQLFKSFRRVRINFSKPEAAARARIELHETDFNGQKLKLYFAQVQMSGEVRDKSYLLPPQPVKQFLISPPASPPVGWKQSEDAMPVINYDLLCAVSKLGPGEKYELHAGTESTPSVVVHVCESETEEEEETKNPKQKIAQTRRPDPPTAALNEPQTFDCAL
研究背景
Inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A. Could play a role during central nervous system development (By similarity).
Highest expression in heart, skeletal muscle kidney, liver and peripheral blood leukocytes. Lower expression in all other tissues.
Interacts with protein phosphatase PPP3CA/calcineurin A.
Belongs to the RCAN family.
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