TFAP2E Antibody - #DF15650
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
折りたたみ／展開
Activating enhancer binding protein 2 epsilon; Activating enhancer-binding protein 2-epsilon; Adaptor related protein complex 2 epsilon subunit; AP 2E; AP2 epsilon; AP2-epsilon; AP2E; AP2E_HUMAN; MGC49007; TFAP 2E; TFAP2E; Transcription factor AP 2 epsilon (activating enhancer binding protein 2 epsilon); Transcription factor AP 2 epsilon; Transcription factor AP-2-epsilon;
免疫原
A synthesized peptide derived from human TFAP2E.
Expressed in skin, primary keratinocytes, immortalized keratinocytes, and HeLa cell line.
- Q6VUC0 AP2E_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MLVHTYSAMERPDGLGAAAGGARLSSLPQAAYGPAPPLCHTPAATAAAEFQPPYFPPPYPQPPLPYGQAPDAAAAFPHLAGDPYGGLAPLAQPQPPQAAWAAPRAAARAHEEPPGLLAPPARALGLDPRRDYATAVPRLLHGLADGAHGLADAPLGLPGLAAAPGLEDLQAMDEPGMSLLDQSVIKKVPIPSKASSLSALSLAKDSLVGGITNPGEVFCSVPGRLSLLSSTSKYKVTVGEVQRRLSPPECLNASLLGGVLRRAKSKNGGRCLRERLEKIGLNLPAGRRKAANVTLLTSLVEGEAVHLARDFGYVCETEFPAKAAAEYLCRQHADPGELHSRKSMLLAAKQICKEFADLMAQDRSPLGNSRPALILEPGVQSCLTHFSLITHGFGGPAICAALTAFQNYLLESLKGLDKMFLSSVGSGHGETKASEKDAKHRK
研究背景
Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP-2-epsilon may play a role in the development of the CNS and in cartilage differentiation (By similarity).
Nucleus.
Expressed in skin, primary keratinocytes, immortalized keratinocytes, and HeLa cell line.
Binds DNA as a dimer. Can form homodimers or heterodimers with other AP-2 family members (By similarity).
Belongs to the AP-2 family.
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