TMEFF1 Antibody - #DF15812

製品: TMEFF1 Antibody
カタログ: DF15812
タンパク質の説明: Rabbit polyclonal antibody to TMEFF1
アプリケーション: ELISA(peptide)
反応性: Human, Mouse, Rat
分子量: 41kD(Calculated).
ユニプロット: Q8IYR6

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関連ダウンロード
MS Report
HPLC Report
MSDS
説明書
COA
プロトコル
WB Handbook
IHC Protocol
IF/ICC Protocol

製品説明

ソース:
Rabbit
アプリケーション:
ELISA(peptide) 1:20000-1:40000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse,Rat
クローナリティ:
Polyclonal
特異性:
TMEFF1 Antibody detects endogenous levels of TMEFF1.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ／展開

C9orf2; C9orf3 TMEFF1; C9orf30 TMEFF1; C9orf30 TMEFF1 fusion protein; Cancer/testis antigen family 120 member 1; CT120.1; H 7365; H7365; MSANTD3-TMEFF1 readthrough; TEFF 1; TEFF1; TEFF1_HUMAN; TMEFF 1; TMEFF1; Tomoregulin-1; Tomoregulin-1 precursor; TR 1; TR-1; TR1; Transmembrane protein with EGF like and two follistatin like domains 1; Transmembrane protein with EGF-like and one follistatin-like domain;

免疫原

免疫原:

A synthesized peptide derived from human TMEFF1.

Uniprot:

Q8IYR6(TEFF1_HUMAN) >>Visit HPA database.

遺伝子(ID):
TMEFF1(100526694)
発現特異性:
Q8IYR6 TEFF1_HUMAN:

Expressed predominantly in brain, and at lower levels in heart, placenta and skeletal muscle. Down-regulated in brain tumors as compared to control brain tissues.

タンパク質配列:
MGAAAAEAPLRLPAAPPLAFCCYTSVLLLFAFSLPGSRASNQPPGGGGGSGGDCPGGKGKSINCSELNVRESDVRVCDESSCKYGGVCKEDGDGLKCACQFQCHTNYIPVCGSNGDTYQNECFLRRAACKHQKEITVIARGPCYSDNGSGSGEGEEEGSGAEVHRKHSKCGPCKYKAECDEDAENVGCVCNIDCSGYSFNPVCASDGSSYNNPCFVREASCIKQEQIDIRHLGHCTDTDDTSLLGKKDDGLQYRPDVKDASDQREDVYIGNHMPCPENLNGYCIHGKCEFIYSTQKASCRCESGYTGQHCEKTDFSILYVVPSRQKLTHVLIAAIIGAVQIAIIVAIVMCITRKCPKNNRGRRQKQNLGHFTSDTSSRMV

研究背景

機能:

May inhibit NODAL and BMP signaling during neural patterning (By similarity). May be a tumor suppressor in brain cancers.

細胞の位置付け:

Cell membrane>Single-pass type I membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Expressed predominantly in brain, and at lower levels in heart, placenta and skeletal muscle. Down-regulated in brain tumors as compared to control brain tissues.

サブユニット構造:

May interact with ST14.

タンパク質ファミリー:

Belongs to the tomoregulin family.

Restrictive clause

 

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