製品: TNNI1 Antibody
カタログ: DF15907
タンパク質の説明: Rabbit polyclonal antibody to TNNI1
アプリケーション: IHC
反応性: Human, Mouse, Rat
分子量: 22kD(Calculated).
ユニプロット: P19237

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製品説明

ソース:
Rabbit
アプリケーション:
IHC 1:50-1:200
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse,Rat
クローナリティ:
Polyclonal
特異性:
TNNI1 Antibody detects endogenous levels of TNNI1.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin.
保存:
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

2700018B22Rik; AI747285; DKFZp451O223; si:dz182n13.3; slow skeletal muscle; slow-twitch isoform; SSTNI; TNN1; Tnni1; TNNI1_HUMAN; Troponin I; Troponin I slow skeletal muscle; Troponin I slow twitch isoform; troponin I type 1 (skeletal, slow); Troponin I, slow isoform;

免疫原

免疫原:

A synthesized peptide derived from human TNNI1.

Uniprot:
遺伝子(ID):
発現特異性:
P19237 TNNI1_HUMAN:

Highest levels observed in human skeletal muscle (e.g. gastrocnemious muscle), differentiated cultures of primary human muscle cells and rhabdomyosarcoma cells cultured in low serum medium. Expressed in C2 muscle cell myoblasts and myotubes.

タンパク質配列:
MPEVERKPKITASRKLLLKSLMLAKAKECWEQEHEEREAEKVRYLAERIPTLQTRGLSLSALQDLCRELHAKVEVVDEERYDIEAKCLHNTREIKDLKLKVMDLRGKFKRPPLRRVRVSADAMLRALLGSKHKVSMDLRANLKSVKKEDTEKERPVEVGDWRKNVEAMSGMEGRKKMFDAAKSPTSQ

研究背景

機能:

Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.

組織特異性:

Highest levels observed in human skeletal muscle (e.g. gastrocnemious muscle), differentiated cultures of primary human muscle cells and rhabdomyosarcoma cells cultured in low serum medium. Expressed in C2 muscle cell myoblasts and myotubes.

タンパク質ファミリー:

Belongs to the troponin I family.

Restrictive clause

 

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