ARFGAP2 Antibody - #DF15939
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
折りたたみ/展開
ADP-ribosylation factor GTPase-activating protein 2; ARF GAP 2; ARFG2_HUMAN; ARFGAP2; FLJ14576; FLJ26000; GTPase activating protein ZNF289; GTPase-activating protein ZNF289; IRZ; Nbla10535; Zfp289; Zinc finger protein 289; Zinc finger protein 289 ID1 regulated; ZNF289;
免疫原
A synthesized peptide derived from human ARFGAP2.
- Q8N6H7 ARFG2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAAEPNKTEIQTLFKRLRAVPTNKACFDCGAKNPSWASITYGVFLCIDCSGVHRSLGVHLSFIRSTELDSNWNWFQLRCMQVGGNANATAFFRQHGCTANDANTKYNSRAAQMYREKIRQLGSAALARHGTDLWIDNMSSAVPNHSPEKKDSDFFTEHTQPPAWDAPATEPSGTQQPAPSTESSGLAQPEHGPNTDLLGTSPKASLELKSSIIGKKKPAAAKKGLGAKKGLGAQKVSSQSFSEIERQAQVAEKLREQQAADAKKQAEESMVASMRLAYQELQIDRKKEEKKLQNLEGKKREQAERLGMGLVSRSSVSHSVLSEMQVIEQETPVSAKSSRSQLDLFDDVGTFASGPPKYKDNPFSLGESFGSRWDTDAAWGMDRVEEKEPEVTISSIRPISERATNRREVESRSSGLESSEARQKFAGAKAISSDMFFGREVDAEYEARSRLQQLSGSSAISSSDLFGDMDGAHGAGSVSLGNVLPTADIAQFKQGVKSVAGKMAVLANGVMNSLQDRYGSY
研究背景
GTPase-activating protein (GAP) for ADP ribosylation factor 1 (ARF1). Implicated in coatomer-mediated protein transport between the Golgi complex and the endoplasmic reticulum. Hydrolysis of ARF1-bound GTP may lead to dissociation of coatomer from Golgi-derived membranes to allow fusion with target membranes.
Cytoplasm. Golgi apparatus membrane>Peripheral membrane protein>Cytoplasmic side.
Note: Also found on peripheral punctate structures likely to be endoplasmic reticulum-Golgi intermediate compartment.
Interacts with the coatomer complex. Interacts with the C-terminal appendage domain of COPG1.
研究領域
· Cellular Processes > Transport and catabolism > Endocytosis. (View pathway)
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