EXTL2 Antibody - #DF16070
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
折りたたみ／展開
4-N-acetylhexosaminyltransferase EXTL2; Alpha 1 4 N acetylhexosaminyltransferase EXTL2; Alpha GalNAcT EXTL2; Alpha-1; Alpha-GalNAcT EXTL2; Exostoses (multiple) like 2; Exostoses multiple like 2; Exostosin like 2; Exostosin like glycosyltransferase 2; EXT L2; EXT related protein 2; EXT-related protein 2; EXTL 2; EXTL2; EXTL2_HUMAN; EXTR 2; EXTR2; Glucuronyl galactosyl proteoglycan 4 alpha N acetylglucosaminyltransferase; Glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase; Multiple exostoses like 2; Processed exostosin like 2; Processed exostosin-like 2;
免疫原
A synthesized peptide derived from human EXTL2.
- Q9UBQ6 EXTL2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MRCCHICKLPGRVMGIRVLRLSLVVILVLLLVAGALTALLPSVKEDKMLMLRREIKSQGKSTMDSFTLIMQTYNRTDLLLKLLNHYQAVPNLHKVIVVWNNIGEKAPDELWNSLGPHPIPVIFKQQTANRMRNRLQVFPELETNAVLMVDDDTLISTPDLVFAFSVWQQFPDQIVGFVPRKHVSTSSGIYSYGSFEMQAPGSGNGDQYSMVLIGASFFNSKYLELFQRQPAAVHALIDDTQNCDDIAMNFIIAKHIGKTSGIFVKPVNMDNLEKETNSGYSGMWHRAEHALQRSYCINKLVNIYDSMPLRYSNIMISQFGFPYANYKRKI
研究背景
Glycosyltransferase required for the biosynthesis of heparan-sulfate and responsible for the alternating addition of beta-1-4-linked glucuronic acid (GlcA) and alpha-1-4-linked N-acetylglucosamine (GlcNAc) units to nascent heparan sulfate chains.
The soluble form derives from the membrane form by proteolytic processing.
Endoplasmic reticulum membrane>Single-pass type II membrane protein.
Secreted.
Note: A soluble form is found in the serum.
Ubiquitous.
Belongs to the glycosyltransferase 47 family.
研究領域
· Metabolism > Glycan biosynthesis and metabolism > Glycosaminoglycan biosynthesis - heparan sulfate / heparin.
· Metabolism > Global and overview maps > Metabolic pathways.
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