KIR3DL2 Antibody - #DF16073
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
折りたたみ／展開
CD158 antigen like family member K; CD158 antigen-like family member K; CD158k; KI3L2_HUMAN; Killer cell immunoglobulin like receptor 3DL2; killer cell immunoglobulin like receptor KIR3DL2; Killer cell immunoglobulin like receptor, three domains, long cytoplasmic tail, 2; Killer cell immunoglobulin-like receptor 3DL2; KIR antigen 3DL2; KIR3DL2; Kirl2; MHC class I NK cell receptor; Natural killer associated transcript 4; natural killer cell inhibitory receptor; Natural killer-associated transcript 4; NK associated transcript 4; NK associated transcript 4A, included; NK associated transcript 4B, included; NKAT-4; NKAT4; NKAT4B; p140; p70 natural killer cell receptor clone CL 5; p70 natural killer cell receptor clone CL-5; p70 NK receptor CL 5; p70 NK receptor CL-5;
免疫原
A synthesized peptide derived from human KIR3DL2.
- P43630 KI3L2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSLTVVSMACVGFFLLQGAWPLMGGQDKPFLSARPSTVVPRGGHVALQCHYRRGFNNFMLYKEDRSHVPIFHGRIFQESFIMGPVTPAHAGTYRCRGSRPHSLTGWSAPSNPLVIMVTGNHRKPSLLAHPGPLLKSGETVILQCWSDVMFEHFFLHREGISEDPSRLVGQIHDGVSKANFSIGPLMPVLAGTYRCYGSVPHSPYQLSAPSDPLDIVITGLYEKPSLSAQPGPTVQAGENVTLSCSSWSSYDIYHLSREGEAHERRLRAVPKVNRTFQADFPLGPATHGGTYRCFGSFRALPCVWSNSSDPLLVSVTGNPSSSWPSPTEPSSKSGICRHLHVLIGTSVVIFLFILLLFFLLYRWCSNKKNAAVMDQEPAGDRTVNRQDSDEQDPQEVTYAQLDHCVFIQRKISRPSQRPKTPLTDTSVYTELPNAEPRSKVVSCPRAPQSGLEGVF
研究背景
Receptor on natural killer (NK) cells and T cells for MHC class I molecules. Upon binding of peptide-free HLA-F open conformer, negatively regulates NK and T cell effector functions. Acts as a receptor on astrocytes for HLA-F. Through interaction with HLA-F, may protect motor neurons from astrocyte-induced toxicity.
Cell membrane>Single-pass type I membrane protein.
Expressed in astrocytes.
Interacts with peptide-free HLA-F open conformer.
Belongs to the immunoglobulin superfamily.
研究領域
· Human Diseases > Immune diseases > Graft-versus-host disease.
· Organismal Systems > Immune system > Antigen processing and presentation. (View pathway)
· Organismal Systems > Immune system > Natural killer cell mediated cytotoxicity. (View pathway)
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