AFfirm™ TGM2 Mouse Monoclonal Antibody - #BF8037
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
折りたたみ／展開
ALPHA SUBUNIT; C polypeptide; EC 2.3.2.13; epididymis secretory protein Li 45; G alpha h; G[a]h; Gh CLASS G ALPHA h; GNAH; GNAH G PROTEIN; H POLYPEPTIDE; HEL-S-45; Protein glutamine gamma glutamyltransferase 2; Protein-glutamine gamma-glutamyltransferase 2; TG 2; TG(C); TG2; TGase C; TGase H; TGase-2; TgaseII; TGC; TGC GUANINE NUCLEOTIDE BINDING PROTEIN; TGM2; TGM2_HUMAN; Tissue transglutaminase; Transglutaminase 2; Transglutaminase 2 C polypeptide; Transglutaminase C; Transglutaminase H; Transglutaminase-2; tTG; tTGas;
免疫原
A synthesized peptide derived from human TGM2, corresponding to a region within N-terminal amino acids.
- P21980 TGM2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAEELVLERCDLELETNGRDHHTADLCREKLVVRRGQPFWLTLHFEGRNYEASVDSLTFSVVTGPAPSQEAGTKARFPLRDAVEEGDWTATVVDQQDCTLSLQLTTPANAPIGLYRLSLEASTGYQGSSFVLGHFILLFNAWCPADAVYLDSEEERQEYVLTQQGFIYQGSAKFIKNIPWNFGQFEDGILDICLILLDVNPKFLKNAGRDCSRRSSPVYVGRVVSGMVNCNDDQGVLLGRWDNNYGDGVSPMSWIGSVDILRRWKNHGCQRVKYGQCWVFAAVACTVLRCLGIPTRVVTNYNSAHDQNSNLLIEYFRNEFGEIQGDKSEMIWNFHCWVESWMTRPDLQPGYEGWQALDPTPQEKSEGTYCCGPVPVRAIKEGDLSTKYDAPFVFAEVNADVVDWIQQDDGSVHKSINRSLIVGLKISTKSVGRDEREDITHTYKYPEGSSEEREAFTRANHLNKLAEKEETGMAMRIRVGQSMNMGSDFDVFAHITNNTAEEYVCRLLLCARTVSYNGILGPECGTKYLLNLNLEPFSEKSVPLCILYEKYRDCLTESNLIKVRALLVEPVINSYLLAERDLYLENPEIKIRILGEPKQKRKLVAEVSLQNPLPVALEGCTFTVEGAGLTEEQKTVEIPDPVEAGEEVKVRMDLLPLHMGLHKLVVNFESDKLKAVKGFRNVIIGPA
PTMs - P21980 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| A2 | Acetylation | Uniprot | |
| C10 | S-Nitrosylation | Uniprot | |
| C27 | S-Nitrosylation | Uniprot | |
| S56 | Phosphorylation | Uniprot | |
| S60 | Phosphorylation | Uniprot | |
| C98 | S-Nitrosylation | Uniprot | |
| S129 | Phosphorylation | Uniprot | |
| C143 | S-Nitrosylation | Uniprot | |
| Y159 | Phosphorylation | Uniprot | |
| K202 | Acetylation | Uniprot | |
| K205 | Acetylation | Uniprot | |
| S212 | Phosphorylation | Uniprot | |
| S215 | Phosphorylation | P17612 (PRKACA) | Uniprot |
| S216 | Phosphorylation | P17612 (PRKACA) | Uniprot |
| Y219 | Phosphorylation | Uniprot | |
| C230 | S-Nitrosylation | Uniprot | |
| Y245 | Phosphorylation | Uniprot | |
| S250 | Phosphorylation | Uniprot | |
| C269 | S-Nitrosylation | Uniprot | |
| C277 | S-Nitrosylation | Uniprot | |
| C285 | S-Nitrosylation | Uniprot | |
| Y315 | Phosphorylation | Uniprot | |
| C336 | S-Nitrosylation | Uniprot | |
| T368 | Phosphorylation | Uniprot | |
| Y369 | Phosphorylation | Uniprot | |
| C370 | S-Nitrosylation | Uniprot | |
| C371 | S-Nitrosylation | Uniprot | |
| S415 | Phosphorylation | Uniprot | |
| S419 | Phosphorylation | Uniprot | |
| S427 | Phosphorylation | Uniprot | |
| K464 | Ubiquitination | Uniprot | |
| C524 | S-Nitrosylation | Uniprot | |
| S538 | Phosphorylation | Uniprot | |
| S541 | Phosphorylation | Uniprot | |
| C545 | S-Nitrosylation | Uniprot | |
| C554 | S-Nitrosylation | Uniprot | |
| Y575 | Phosphorylation | Uniprot | |
| Y583 | Phosphorylation | Uniprot | |
| K590 | Ubiquitination | Uniprot | |
| S608 | Phosphorylation | Uniprot | |
| C620 | S-Nitrosylation | Uniprot | |
| K649 | Ubiquitination | Uniprot | |
| K672 | Acetylation | Uniprot |
PTMs - P21980 酵素として
| Substrate | Site | Source |
|---|---|---|
| P68431 (HIST1H3J) | S11 | Uniprot |
研究背景
Catalyzes the cross-linking of proteins, such as WDR54, and the conjugation of polyamines to proteins.
Monomer.
Belongs to the transglutaminase superfamily. Transglutaminase family.
研究領域
· Human Diseases > Neurodegenerative diseases > Huntington's disease.
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