製品: FOXJ1 Mouse Monoclonal Antibody
カタログ: BF8040
タンパク質の説明: Mouse monoclonal antibody to FOXJ1
アプリケーション: WB
反応性: Human
予測: Pig, Bovine, Horse, Sheep, Rabbit, Dog
分子量: 60kDa; 45kD(Calculated).
ユニプロット: Q92949

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製品説明

ソース:
Mouse
アプリケーション:
WB 1:500-1:3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human
クローナリティ:
Monoclonal [AFfirm8040(AFP21836)]
特異性:
FOXJ1 Antibody detects endogenous levels of total FOXJ1.
コンジュゲート:
Unconjugated.
精製:
Affinity-chromatography.
保存:
Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

FKHL13; Forkhead box J1; Forkhead box protein J1; Forkhead Homologue 4; Forkhead related protein FKHL13; Forkhead-related protein FKHL13; Fox J1; Foxj1; FOXJ1_HUMAN; Hepatocyte nuclear factor 3 forkhead homolog 4; HFH 4; HFH-4; HFH4; HNF 3/forkhead homolog 4; MGC35202;

免疫原

免疫原:

A synthesized peptide derived from human FOXJ1, corresponding to a region within the internal amino acids.

Uniprot:
遺伝子(ID):
発現特異性:
Q92949 FOXJ1_HUMAN:

Testis, oviduct, lung and brain cortex.

タンパク質の説明:
FOXJ1 May play an important role in cell fate determination during lung development and in spermatogenesis. Note:
タンパク質配列:
MAESWLRLSGAGPAEEAGPEGGLEEPDALDDSLTSLQWLQEFSILNAKAPALPPGGTDPHGYHQVPGSAAPGSPLAADPACLGQPHTPGKPTSSCTSRSAPPGLQAPPPDDVDYATNPHVKPPYSYATLICMAMQASKATKITLSAIYKWITDNFCYFRHADPTWQNSIRHNLSLNKCFIKVPREKDEPGKGGFWRIDPQYAERLLSGAFKKRRLPPVHIHPAFARQAAQEPSAVPRAGPLTVNTEAQQLLREFEEATGEAGWGAGEGRLGHKRKQPLPKRVAKVPRPPSTLLPTPEEQGELEPLKGNFDWEAIFDAGTLGGELGALEALELSPPLSPASHVDVDLTIHGRHIDCPATWGPSVEQAADSLDFDETFLATSFLQHPWDESGSGCLPPEPLFEAGDATLASDLQDWASVGAFL

PTMs - Q92949 基板として

Site PTM Type Enzyme
S174 Phosphorylation

研究背景

機能:

Transcription factor specifically required for the formation of motile cilia. Acts by activating transcription of genes that mediate assembly of motile cilia, such as CFAP157. Binds the DNA consensus sequences 5'-HWDTGTTTGTTTA-3' or 5'-KTTTGTTGTTKTW-3' (where H is not G, W is A or T, D is not C, and K is G or T). Activates the transcription of a variety of ciliary proteins in the developing brain and lung.

細胞の位置付け:

Nucleus.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Testis, oviduct, lung and brain cortex.

タンパク質ファミリー:

Belongs to the FOXJ1 family.

Restrictive clause

 

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