AFfirm™ ALDOA Mouse Monoclonal Antibody - #BF8051
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
折りたたみ／展開
ALDA; Aldo1; ALDOA; ALDOA_HUMAN; Aldolase 1; Aldolase A; Aldolase A fructose bisphosphatase; Aldolase A fructose bisphosphate; Aldolase, fructose-bisphosphate A; Epididymis secretory sperm binding protein Li 87p; FRUCTOALDOLASE A; Fructose 1 6 bisphosphate triosephosphate lyase; Fructose bisphosphate aldolase A; Fructose bisphosphate aldolase; FRUCTOSE-1,6-BISPHOSPHATE ALDOLASE A; Fructose-bisphosphate aldolase A; Fructose-bisphosphate aldolase A Muscle-type; GSD12; HEL S 87p; Lung cancer antigen NY LU 1; Lung cancer antigen NY-LU-1; MGC10942; MGC17716; MGC17767; Muscle type aldolase; Muscle-type aldolase; RNALDOG5;
免疫原
A synthesized peptide derived from human ALDOA, corresponding to a region within N-terminal amino acids.
- P04075 ALDOA_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MPYQYPALTPEQKKELSDIAHRIVAPGKGILAADESTGSIAKRLQSIGTENTEENRRFYRQLLLTADDRVNPCIGGVILFHETLYQKADDGRPFPQVIKSKGGVVGIKVDKGVVPLAGTNGETTTQGLDGLSERCAQYKKDGADFAKWRCVLKIGEHTPSALAIMENANVLARYASICQQNGIVPIVEPEILPDGDHDLKRCQYVTEKVLAAVYKALSDHHIYLEGTLLKPNMVTPGHACTQKFSHEEIAMATVTALRRTVPPAVTGITFLSGGQSEEEASINLNAINKCPLLKPWALTFSYGRALQASALKAWGGKKENLKAAQEEYVKRALANSLACQGKYTPSGQAGAAASESLFVSNHAY
PTMs - P04075 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| Y3 | Phosphorylation | Uniprot | |
| Y5 | Phosphorylation | Uniprot | |
| T9 | Phosphorylation | Uniprot | |
| K13 | Acetylation | Uniprot | |
| K13 | Ubiquitination | Uniprot | |
| K14 | Acetylation | Uniprot | |
| K14 | Ubiquitination | Uniprot | |
| S17 | Phosphorylation | Uniprot | |
| K28 | Ubiquitination | Uniprot | |
| S36 | Phosphorylation | Uniprot | |
| T37 | Phosphorylation | Uniprot | |
| S39 | Phosphorylation | Uniprot | |
| K42 | Acetylation | Uniprot | |
| K42 | Sumoylation | Uniprot | |
| K42 | Ubiquitination | Uniprot | |
| S46 | Phosphorylation | Uniprot | |
| T49 | Phosphorylation | Uniprot | |
| T52 | Phosphorylation | Uniprot | |
| R56 | Methylation | Uniprot | |
| T65 | Phosphorylation | Uniprot | |
| R69 | Methylation | Uniprot | |
| C73 | S-Nitrosylation | Uniprot | |
| K87 | Ubiquitination | Uniprot | |
| K99 | Methylation | Uniprot | |
| K99 | Ubiquitination | Uniprot | |
| S100 | Phosphorylation | Uniprot | |
| K101 | Methylation | Uniprot | |
| K101 | Ubiquitination | Uniprot | |
| K108 | Acetylation | Uniprot | |
| K108 | Sumoylation | Uniprot | |
| K108 | Ubiquitination | Uniprot | |
| K111 | Acetylation | Uniprot | |
| K111 | Ubiquitination | Uniprot | |
| S132 | Phosphorylation | Uniprot | |
| R134 | Methylation | Uniprot | |
| Y138 | Phosphorylation | Uniprot | |
| K139 | Acetylation | Uniprot | |
| K139 | Ubiquitination | Uniprot | |
| K140 | Ubiquitination | Uniprot | |
| K147 | Acetylation | Uniprot | |
| K147 | Ubiquitination | Uniprot | |
| K153 | Acetylation | Uniprot | |
| K153 | Ubiquitination | Uniprot | |
| T158 | Phosphorylation | Uniprot | |
| S160 | Phosphorylation | Uniprot | |
| Y174 | Phosphorylation | Uniprot | |
| S176 | Phosphorylation | Uniprot | |
| K200 | Acetylation | Uniprot | |
| K200 | Ubiquitination | Uniprot | |
| Y204 | Phosphorylation | Uniprot | |
| T206 | Phosphorylation | Uniprot | |
| K208 | Acetylation | Uniprot | |
| K208 | Ubiquitination | Uniprot | |
| Y214 | Phosphorylation | Uniprot | |
| K215 | Methylation | Uniprot | |
| K215 | Ubiquitination | Uniprot | |
| S218 | Phosphorylation | Uniprot | |
| Y223 | Phosphorylation | Uniprot | |
| T227 | Phosphorylation | Uniprot | |
| K230 | Acetylation | Uniprot | |
| K230 | Ubiquitination | Uniprot | |
| T235 | Phosphorylation | Uniprot | |
| C240 | S-Nitrosylation | Uniprot | |
| T241 | Phosphorylation | Uniprot | |
| T269 | Phosphorylation | Uniprot | |
| S272 | Phosphorylation | Uniprot | |
| S276 | Phosphorylation | Uniprot | |
| K294 | Acetylation | Uniprot | |
| K294 | Methylation | Uniprot | |
| K294 | Ubiquitination | Uniprot | |
| T299 | Phosphorylation | Uniprot | |
| S301 | Phosphorylation | Uniprot | |
| S309 | Phosphorylation | Uniprot | |
| K312 | Acetylation | Uniprot | |
| K312 | Methylation | Uniprot | |
| K312 | Ubiquitination | Uniprot | |
| K318 | Ubiquitination | Uniprot | |
| K322 | Acetylation | Uniprot | |
| K322 | Methylation | Uniprot | |
| K322 | Ubiquitination | Uniprot | |
| Y328 | Phosphorylation | Uniprot | |
| K330 | Acetylation | Uniprot | |
| K330 | Ubiquitination | Uniprot | |
| S336 | Phosphorylation | Uniprot | |
| C339 | S-Nitrosylation | Uniprot | |
| K342 | Acetylation | Uniprot | |
| K342 | Ubiquitination | Uniprot | |
| Y343 | Phosphorylation | Uniprot | |
| T344 | Phosphorylation | Uniprot | |
| S346 | Phosphorylation | Uniprot | |
| S354 | Phosphorylation | Uniprot | |
| S356 | Phosphorylation | Uniprot | |
| S360 | Phosphorylation | Uniprot | |
| Y364 | Phosphorylation | Uniprot |
研究背景
Plays a key role in glycolysis and gluconeogenesis. In addition, may also function as scaffolding protein (By similarity).
Cytoplasm>Myofibril>Sarcomere>I band. Cytoplasm>Myofibril>Sarcomere>M line.
Note: In skeletal muscle, accumulates around the M line and within the I band, colocalizing with FBP2 on both sides of the Z line in the absence of Ca(2+).
Homotetramer. Interacts with SNX9 and WAS (By similarity). Interacts with FBP2; the interaction blocks FBP2 inhibition by physiological concentrations of AMP and reduces inhibition by Ca(2+).
Belongs to the class I fructose-bisphosphate aldolase family.
研究領域
· Environmental Information Processing > Signal transduction > HIF-1 signaling pathway. (View pathway)
· Metabolism > Carbohydrate metabolism > Glycolysis / Gluconeogenesis.
· Metabolism > Carbohydrate metabolism > Pentose phosphate pathway.
· Metabolism > Carbohydrate metabolism > Fructose and mannose metabolism.
· Metabolism > Global and overview maps > Metabolic pathways.
· Metabolism > Global and overview maps > Carbon metabolism.
· Metabolism > Global and overview maps > Biosynthesis of amino acids.
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