AFfirm™ BCL7B Mouse Monoclonal Antibody - #BF8098
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
折りたたみ／展開
B cell CLL/lymphoma 7 protein family member B; B cell CLL/lymphoma 7B; B-cell CLL/lymphoma 7 protein family member B; BCL 7B; BCL7B; BCL7B_HUMAN;
免疫原
- Q9BQE9 BCL7B_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSGRSVRAETRSRAKDDIKKVMAAIEKVRKWEKKWVTVGDTSLRIFKWVPVTDSKEKEKSKSNSSAAREPNGFPSDASANSSLLLEFQDENSNQSSVSDVYQLKVDSSTNSSPSPQQSESLSPAHTSDFRTDDSQPPTLGQEILEEPSLPSSEVADEPPTLTKEEPVPLETQVVEEEEDSGAPPLKRFCVDQPTVPQTASES
PTMs - Q9BQE9 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K27 | Ubiquitination | Uniprot | |
| K34 | Ubiquitination | Uniprot | |
| T41 | Phosphorylation | Uniprot | |
| S107 | Phosphorylation | Uniprot | |
| S108 | Phosphorylation | Uniprot | |
| T109 | Phosphorylation | Uniprot | |
| S112 | Phosphorylation | Uniprot | |
| S114 | Phosphorylation | Uniprot | |
| S118 | Phosphorylation | Uniprot | |
| S120 | Phosphorylation | Uniprot | |
| S122 | Phosphorylation | Uniprot | |
| T126 | Phosphorylation | Uniprot | |
| S127 | Phosphorylation | Uniprot | |
| T131 | Phosphorylation | Uniprot | |
| S134 | Phosphorylation | Uniprot | |
| S180 | Phosphorylation | Uniprot | |
| K186 | Ubiquitination | Uniprot | |
| C189 | S-Nitrosylation | Uniprot | |
| T194 | Phosphorylation | Uniprot | |
| S200 | Phosphorylation | Uniprot |
研究背景
Positive regulator of apoptosis. Plays a role in the Wnt signaling pathway, negatively regulating the expression of Wnt signaling components CTNNB1 and HMGA1. Involved in cell cycle progression, maintenance of the nuclear structure and stem cell differentiation. May play a role in lung tumor development or progression (By similarity).
Ubiquitous.
Belongs to the BCL7 family.
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