AFfirm™ EEF1A2 Mouse Monoclonal Antibody - #BF8103

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製品: EEF1A2 Mouse Monoclonal Antibody
カタログ: BF8103
タンパク質の説明: Mouse monoclonal antibody to EEF1A2
アプリケーション: WB
反応性: Human
予測: Pig, Bovine, Horse, Sheep, Rabbit, Chicken, Xenopus
分子量: 50 kDa; 50kD(Calculated).
ユニプロット: Q05639

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製品説明

ソース:
Mouse
アプリケーション:
WB 1:500-1:3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human
クローナリティ:
Monoclonal [AFfirm8103]
特異性:
EEF1A2 Antibody detects endogenous levels of total EEF1A2.
コンジュゲート:
Unconjugated.
精製:
Affinity-chromatography.
保存:
Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ／展開

CCS3; eEF1A-1; eEF1A-2; EEF1A1; Eef1a2; EEF1AL; EF 1 alpha 2; EF-1-alpha-1; EF-1-alpha-2; EF-Tu; EF1A; EF1A1_HUMAN; EF1A2_HUMAN; Elongation factor 1 A 2; Elongation factor 1 alpha; Elongation factor 1 alpha 2; Elongation factor 1-alpha 1; Elongation factor 1-alpha 2; Elongation factor Tu; Eukaryotic elongation factor 1 A-1; Eukaryotic elongation factor 1 A-2; Eukaryotic translation elongation factor 1 alpha 2; GRAF 1EF; HS1; Leukocyte receptor cluster member 7; PTI1; Statin-S1;

免疫原

免疫原:

A synthesized peptide derived from human EEF1A2, corresponding to a region within the internal amino acids.

Uniprot:

Q05639(EF1A2_HUMAN) >>Visit HPA database.

遺伝子(ID):
EEF1A2(1917)
発現特異性:
Q05639 EF1A2_HUMAN:

Brain, heart, and skeletal muscle.

タンパク質配列:
MGKEKTHINIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAAEMGKGSFKYAWVLDKLKAERERGITIDISLWKFETTKYYITIIDAPGHRDFIKNMITGTSQADCAVLIVAAGVGEFEAGISKNGQTREHALLAYTLGVKQLIVGVNKMDSTEPAYSEKRYDEIVKEVSAYIKKIGYNPATVPFVPISGWHGDNMLEPSPNMPWFKGWKVERKEGNASGVSLLEALDTILPPTRPTDKPLRLPLQDVYKIGGIGTVPVGRVETGILRPGMVVTFAPVNITTEVKSVEMHHEALSEALPGDNVGFNVKNVSVKDIRRGNVCGDSKSDPPQEAAQFTSQVIILNHPGQISAGYSPVIDCHTAHIACKFAELKEKIDRRSGKKLEDNPKSLKSGDAAIVEMVPGKPMCVESFSQYPPLGRFAVRDMRQTVAVGVIKNVEKKSGGAGKVTKSAQKAQKAGK

研究背景

機能:

This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.

PTMs:

Trimethylated at Lys-165 by EEF1AKMT3. Mono-, di-, and trimethylated at Lys-36 by EEF1AKMT4; trimethylated form is predominant. Methylation by EEF1AKMT4 contributes to the fine-tuning of translation rates for a subset of tRNAs. Trimethylated at the N-terminus by EEF1AKNMT. Mono- and dimethylated at Lys-55 by EEF1AKNMT; dimethylated form is predominant.

細胞の位置付け:

Nucleus.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Brain, heart, and skeletal muscle.

タンパク質ファミリー:

Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.

研究領域

· Genetic Information Processing > Translation > RNA transport.

· Human Diseases > Infectious diseases: Bacterial > Legionellosis.

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