製品: SAF-A2 Mouse Monoclonal Antibody
カタログ: BF8463
タンパク質の説明: Mouse monoclonal antibody to SAF-A2
アプリケーション: WB IHC
反応性: Human, Rat
予測: Pig, Bovine, Sheep, Dog
分子量: 85,100kDa; 85kD(Calculated).
ユニプロット: Q1KMD3

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製品説明

ソース:
Mouse
アプリケーション:
WB 1:500-1:3000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Rat
クローナリティ:
Monoclonal [AFfirm8463]
コンジュゲート:
Unconjugated.
精製:
Affinity-chromatography.
保存:
Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

DKFZp762N1910; Heterogeneous nuclear ribonucleoprotein U like 2; Heterogeneous nuclear ribonucleoprotein U like protein 2; Heterogeneous nuclear ribonucleoprotein U-like protein 2; HNRL2_HUMAN; HNRNPUL 2; HNRNPUL2; HNRPUL2; OTTHUMP00000236813; SAF A2; SAF-A2; Scaffold attachment factor A2; Scaffold-attachment factor A2;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
タンパク質配列:
MEVKRLKVTELRSELQRRGLDSRGLKVDLAQRLQEALDAEMLEDEAGGGGAGPGGACKAEPRPVAASGGGPGGDEEEDEEEEEEDEEALLEDEDEEPPPAQALGQAAQPPPEPPEAAAMEAAAEPDASEKPAEATAGSGGVNGGEEQGLGKREEDEPEERSGDETPGSEVPGDKAAEEQGDDQDSEKSKPAGSDGERRGVKRQRDEKDEHGRAYYEFREEAYHSRSKSPLPPEEEAKDEEEDQTLVNLDTYTSDLHFQVSKDRYGGQPLFSEKFPTLWSGARSTYGVTKGKVCFEAKVTQNLPMKEGCTEVSLLRVGWSVDFSRPQLGEDEFSYGFDGRGLKAENGQFEEFGQTFGENDVIGCFANFETEEVELSFSKNGEDLGVAFWISKDSLADRALLPHVLCKNCVVELNFGQKEEPFFPPPEEFVFIHAVPVEERVRTAVPPKTIEECEVILMVGLPGSGKTQWALKYAKENPEKRYNVLGAETVLNQMRMKGLEEPEMDPKSRDLLVQQASQCLSKLVQIASRTKRNFILDQCNVYNSGQRRKLLLFKTFSRKVVVVVPNEEDWKKRLELRKEVEGDDVPESIMLEMKANFSLPEKCDYMDEVTYGELEKEEAQPIVTKYKEEARKLLPPSEKRTNRRNNRNKRNRQNRSRGQGYVGGQRRGYDNRAYGQQYWGQPGNRGGYRNFYDRYRGDYDRFYGRDYEYNRYRDYYRQYNRDWQSYYYHHPQDRDRYYRNYYGYQGYR

PTMs - Q1KMD3 基板として

Site PTM Type Enzyme
K4 Acetylation
K7 Acetylation
R23 Methylation
K26 Ubiquitination
C57 S-Nitrosylation
K58 Acetylation
S67 Phosphorylation
S138 Phosphorylation
R160 Methylation
S161 Phosphorylation
T165 Phosphorylation
S168 Phosphorylation
K174 Ubiquitination
S185 Phosphorylation
K187 Ubiquitination
S188 Phosphorylation
S193 Phosphorylation
Y214 Phosphorylation
Y222 Phosphorylation
S224 Phosphorylation
S226 Phosphorylation
S228 Phosphorylation
T244 Phosphorylation
T250 Phosphorylation
T252 Phosphorylation
S253 Phosphorylation
K261 Ubiquitination
S271 Phosphorylation
K273 Acetylation
K273 Ubiquitination
K289 Ubiquitination
K291 Ubiquitination
K297 Ubiquitination
K305 Acetylation
K305 Ubiquitination
K342 Sumoylation
R397 Methylation
K406 Ubiquitination
T442 Phosphorylation
K471 Acetylation
K471 Ubiquitination
Y481 Phosphorylation
R494 Methylation
K496 Ubiquitination
K506 Ubiquitination
S516 Phosphorylation
K521 Ubiquitination
C538 S-Nitrosylation
S543 Phosphorylation
K548 Ubiquitination
K553 Acetylation
K553 Ubiquitination
K558 Ubiquitination
K570 Acetylation
K570 Ubiquitination
K571 Acetylation
S597 Phosphorylation
K601 Ubiquitination
Y604 Phosphorylation
Y610 Phosphorylation
K624 Ubiquitination
Y625 Phosphorylation
K631 Ubiquitination
S636 Phosphorylation
K638 Ubiquitination
S655 Phosphorylation
R656 Methylation
R666 Methylation
R671 Methylation
R684 Methylation
R688 Methylation
R693 Methylation
R695 Methylation
Y698 Phosphorylation
R700 Methylation
R704 Methylation
Y706 Phosphorylation
R716 Methylation
R720 Methylation
Y725 Phosphorylation
Y726 Phosphorylation
Y727 Phosphorylation
R738 Methylation
Y740 Phosphorylation
Y743 Phosphorylation
Y746 Phosphorylation
R747 Methylation

研究背景

細胞の位置付け:

Nucleus.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
サブユニット構造:

Binds to MLF1 and retains it in the nucleus.

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