AFfirm™ Semaphorin 3B Mouse Monoclonal Antibody - #BF8482

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製品: Semaphorin 3B Mouse Monoclonal Antibody
カタログ: BF8482
タンパク質の説明: Mouse monoclonal antibody to Semaphorin 3B
アプリケーション: WB IHC IF/ICC
反応性: Human, Rat
分子量: 50,80kD; 83kD(Calculated).
ユニプロット: Q13214

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MS Report
HPLC Report
MSDS
説明書
COA
プロトコル
WB Handbook
IHC Protocol
IF/ICC Protocol

製品説明

ソース:
Mouse
アプリケーション:
WB 1:500-1:3000, IHC 1:50-1:200, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Rat
クローナリティ:
Monoclonal [AFfirm8482]
コンジュゲート:
Unconjugated.
精製:
Affinity-chromatography.
保存:
Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ／展開

SEM3B_HUMAN; Sema A(V); Sema V; Sema3b; Semaphorin V; Semaphorin-3B; Semaphorin-V;

免疫原

免疫原:

A synthesized peptide derived from Human Semaphorin 3B.

Uniprot:

Q13214(SEM3B_HUMAN) >>Visit HPA database.

遺伝子(ID):
SEMA3B(7869)
発現特異性:
Q13214 SEM3B_HUMAN:

Expressed abundantly but differentially in a variety of neural and nonneural tissues.

タンパク質配列:
MGRAGAAAVIPGLALLWAVGLGSAAPSPPRLRLSFQELQAWHGLQTFSLERTCCYQALLVDEERGRLFVGAENHVASLNLDNISKRAKKLAWPAPVEWREECNWAGKDIGTECMNFVKLLHAYNRTHLLACGTGAFHPTCAFVEVGHRAEEPVLRLDPGRIEDGKGKSPYDPRHRAASVLVGEELYSGVAADLMGRDFTIFRSLGQRPSLRTEPHDSRWLNEPKFVKVFWIPESENPDDDKIYFFFRETAVEAAPALGRLSVSRVGQICRNDVGGQRSLVNKWTTFLKARLVCSVPGVEGDTHFDQLQDVFLLSSRDHRTPLLYAVFSTSSSIFQGSAVCVYSMNDVRRAFLGPFAHKEGPMHQWVSYQGRVPYPRPGMCPSKTFGTFSSTKDFPDDVIQFARNHPLMYNSVLPTGGRPLFLQVGANYTFTQIAADRVAAADGHYDVLFIGTDVGTVLKVISVPKGSRPSAEGLLLEELHVFEDSAAVTSMQISSKRHQLYVASRSAVAQIALHRCAAHGRVCTECCLARDPYCAWDGVACTRFQPSAKRRFRRQDVRNGDPSTLCSGDSSRPALLEHKVFGVEGSSAFLECEPRSLQARVEWTFQRAGVTAHTQVLAEERTERTARGLLLRRLRRRDSGVYLCAAVEQGFTQPLRRLSLHVLSATQAERLARAEEAAPAAPPGPKLWYRDFLQLVEPGGGGSANSLRMCRPQPALQSLPLESRRKGRNRRTHAPEPRAERGPRSATHW

研究背景

機能:

Inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons.

細胞の位置付け:

Secreted. Endoplasmic reticulum.
Note: Accumulates in the endoplasmic reticulum.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Expressed abundantly but differentially in a variety of neural and nonneural tissues.

タンパク質ファミリー:

Belongs to the semaphorin family.

研究領域

· Organismal Systems > Development > Axon guidance.   (View pathway)

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