AFfirm™ Pit1 Mouse Monoclonal Antibody - #BF8489

(6)  
製品: Pit1 Mouse Monoclonal Antibody
カタログ: BF8489
タンパク質の説明: Mouse monoclonal antibody to Pit1
アプリケーション: WB
反応性: Human, Mouse, Rat
分子量: 33,40kD; 33kD(Calculated).
ユニプロット: P28069

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 200ul $350 在庫あり

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関連ダウンロード
MS Report
HPLC Report
MSDS
説明書
COA
プロトコル
WB Handbook
IHC Protocol
IF/ICC Protocol

製品説明

ソース:
Mouse
アプリケーション:
WB 1:500-1:3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse,Rat
クローナリティ:
Monoclonal [AFfirm8489]
コンジュゲート:
Unconjugated.
精製:
Affinity-chromatography.
保存:
Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ／展開

Dwarf; GHF 1; GHF 1A; GHF-1; GHF1; GHF1A; Growth hormone factor 1; Hmp 1; Hmp1; Pit 1; Pit 1 beta; PIT 1Z; PiT-1; Pit1 beta; PIT1_HUMAN; PIT1Z; Pituitary growth hormone; Pituitary specific positive transcription factor 1; Pituitary-specific positive transcription factor 1; POU class 1 homeobox 1; POU domain class 1 transcription factor 1; POU domain transcriptional regulator; POU1F1;

免疫原

免疫原:

A synthesized peptide derived from Human Pit1.

Uniprot:

P28069(PIT1_HUMAN) >>Visit HPA database.

遺伝子(ID):
POU1F1(5449)
タンパク質配列:
MSCQAFTSADTFIPLNSDASATLPLIMHHSAAECLPVSNHATNVMSTATGLHYSVPSCHYGNQPSTYGVMAGSLTPCLYKFPDHTLSHGFPPIHQPLLAEDPTAADFKQELRRKSKLVEEPIDMDSPEIRELEKFANEFKVRRIKLGYTQTNVGEALAAVHGSEFSQTTICRFENLQLSFKNACKLKAILSKWLEEAEQVGALYNEKVGANERKRKRRTTISIAAKDALERHFGEQNKPSSQEIMRMAEELNLEKEVVRVWFCNRRQREKRVKTSLNQSLFSISKEHLECR

研究背景

機能:

Transcription factor involved in the specification of the lactotrope, somatotrope, and thyrotrope phenotypes in the developing anterior pituitary. Specifically binds to the consensus sequence 5'-TAAAT-3'. Activates growth hormone and prolactin genes.

細胞の位置付け:

Nucleus.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
サブユニット構造:

Interacts with PITX1. Interacts with LHX3. Interacts with ELK1.

タンパク質ファミリー:

Belongs to the POU transcription factor family. Class-1 subfamily.

Restrictive clause

 

Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.

For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.