製品: DNALI1 Mouse Monoclonal Antibody
カタログ: BF8499
タンパク質の説明: Mouse monoclonal antibody to DNALI1
アプリケーション: WB IHC IF/ICC
反応性: Human, Mouse, Rat
分子量: 32kD; 30kD(Calculated).
ユニプロット: O14645

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製品説明

ソース:
Mouse
アプリケーション:
WB 1:500-1:3000, IHC 1:50-1:200, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse,Rat
クローナリティ:
Monoclonal [AFfirm8499]
コンジュゲート:
Unconjugated.
精製:
Affinity-chromatography.
保存:
Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

axonemal; Axonemal dynein light chain (hp28); Axonemal dynein light chain; Axonemal dynein light intermediate polypeptide 1; dJ423B22.5; DNALI 1; DNALI1; Dynein axonemal light intermediate chain 1; Dynein axonemal light intermediate polypeptide 1; hp28; IDLC_HUMAN; Inner dynein arm homolog of clamydomonas; Inner dynein arm light chain; Inner dynein arm light chain axonemal; P28;

免疫原

免疫原:

A synthesized peptide derived from Human DNALI1.

Uniprot:
遺伝子(ID):
発現特異性:
O14645 IDLC_HUMAN:

Expressed in many tissues. A smaller 0.9 kb and a larger 2.5 kb transcripts were detected at the highest level in the testis, at medium levels in the prostate, heart, liver, lung and pancreas, at low levels in the ovary, skeletal muscle and small intestine. Not detected in spleen, colon epithelium, thymus or peripheral blood leukocytes. The 0.9 kb transcript is expressed at a 20-fold higher level than the 2.5 kb transcript in the testis.

タンパク質配列:
MIPPADSLLKYDTPVLVSRNTEKRSPKARLLKVSPQQPGPSGSAPQPPKTKLPSTPCVPDPTKQAEEILNAILPPREWVEDTQLWIQQVSSTPSTRMDVVHLQEQLDLKLQQRQARETGICPVRRELYSQCFDELIREVTINCAERGLLLLRVRDEIRMTIAAYQTLYESSVAFGMRKALQAEQGKSDMERKIAELETEKRDLERQVNEQKAKCEATEKRESERRQVEEKKHNEEIQFLKRTNQQLKAQLEGIIAPKK

研究背景

機能:

May play a dynamic role in flagellar motility.

細胞の位置付け:

Cell projection>Cilium.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Expressed in many tissues. A smaller 0.9 kb and a larger 2.5 kb transcripts were detected at the highest level in the testis, at medium levels in the prostate, heart, liver, lung and pancreas, at low levels in the ovary, skeletal muscle and small intestine. Not detected in spleen, colon epithelium, thymus or peripheral blood leukocytes. The 0.9 kb transcript is expressed at a 20-fold higher level than the 2.5 kb transcript in the testis.

タンパク質ファミリー:

Belongs to the inner dynein arm light chain family.

研究領域

· Human Diseases > Neurodegenerative diseases > Huntington's disease.

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