AFfirm™ SDF4 Mouse Monoclonal Antibody - #BF8500

(5)  
製品: SDF4 Mouse Monoclonal Antibody
カタログ: BF8500
タンパク質の説明: Mouse monoclonal antibody to SDF4
アプリケーション: WB IHC
反応性: Human
分子量: 30~40kD; 42kD(Calculated).
ユニプロット: Q9BRK5

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関連ダウンロード
MS Report
HPLC Report
MSDS
説明書
COA
プロトコル
WB Handbook
IHC Protocol
IF/ICC Protocol

製品説明

ソース:
Mouse
アプリケーション:
WB 1:500-1:3000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human
クローナリティ:
Monoclonal [AFfirm8500]
コンジュゲート:
Unconjugated.
精製:
Affinity-chromatography.
保存:
Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ／展開

45 kDa calcium-binding protein; Cab45; CAB45_HUMAN; Calcium binding protein; PSEC0034; SDF 4; SDF-4; SDF4; Stromal cell derived factor 4; Stromal cell-derived factor 4;

免疫原

免疫原:

A synthesized peptide derived from Human SDF4.

Uniprot:

Q9BRK5(CAB45_HUMAN) >>Visit HPA database.

遺伝子(ID):
SDF4(51150)
発現特異性:
Q9BRK5 CAB45_HUMAN:

Ubiquitous. Isoform 5 is expressed in pancreas.

タンパク質配列:
MVWPWVAMASRWGPLIGLAPCCLWLLGAVLLMDASARPANHSSTRERVANREENEILPPDHLNGVKLEMDGHLNRGFHQEVFLGKDLGGFDEDAEPRRSRRKLMVIFSKVDVNTDRKISAKEMQRWIMEKTAEHFQEAMEESKTHFRAVDPDGDGHVSWDEYKVKFLASKGHSEKEVADAIRLNEELKVDEETQEVLENLKDRWYQADSPPADLLLTEEEFLSFLHPEHSRGMLRFMVKEIVRDLDQDGDKQLSVPEFISLPVGTVENQQGQDIDDNWVKDRKKEFEELIDSNHDGIVTAEELESYMDPMNEYNALNEAKQMIAVADENQNHHLEPEEVLKYSEFFTGSKLVDYARSVHEEF

研究背景

機能:

May regulate calcium-dependent activities in the endoplasmic reticulum lumen or post-ER compartment.

Isoform 5 may be involved in the exocytosis of zymogens by pancreatic acini.

細胞の位置付け:

Golgi apparatus lumen.

Cytoplasm. Cell membrane. Cell projection>Bleb.
Note: Isoform 5 colocalizes with STX3 and STXBP1 isoform 2 at the plasma membrane and cell surface blebs.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Ubiquitous. Isoform 5 is expressed in pancreas.

サブユニット構造:

Isoform 5 interacts with STXBP1; the interaction is enhanced in presence of calcium. Isoform 5 interacts with STX3.

タンパク質ファミリー:

Binds calcium via its EF-hands (By similarity). Isoform 5 binds calcium.

Belongs to the CREC family.

Restrictive clause

 

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