製品: HDLBP Mouse Monoclonal Antibody
カタログ: BF8531
タンパク質の説明: Mouse monoclonal antibody to HDLBP
アプリケーション: WB IHC
反応性: Human, Mouse, Rat
予測: Pig, Bovine, Horse, Sheep, Rabbit, Chicken, Xenopus
分子量: 141 kDa; 141kD(Calculated).
ユニプロット: Q00341

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製品説明

ソース:
Mouse
アプリケーション:
WB 1:500-1:3000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse,Rat
クローナリティ:
Monoclonal [AFfirm8531]
コンジュゲート:
Unconjugated.
精製:
Affinity-chromatography.
保存:
Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

HBP; HDL binding protein; HDL-binding protein; HDLBP; high density lipoprotein binding protein; high density lipoprotein binding protein (vigilin); High density lipoprotein-binding protein; PRO2900; VGL; Vigilin; VIGLN_HUMAN;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
タンパク質配列:
MSSVAVLTQESFAEHRSGLVPQQIKVATLNSEEESDPPTYKDAFPPLPEKAACLESAQEPSGAWGNKIRPIKASVITQVFHVPLEERKYKDMNQFGEGEQAKICLEIMQRTGAHLELSLAKDQGLSIMVSGKLDAVMKARKDIVARLQTQASATVAIPKEHHRFVIGKNGEKLQDLELKTATKIQIPRPDDPSNQIKITGTKEGIEKARHEVLLISAEQDKRAVERLEVEKAFHPFIAGPYNRLVGEIMQETGTRINIPPPSVNRTEIVFTGEKEQLAQAVARIKKIYEEKKKKTTTIAVEVKKSQHKYVIGPKGNSLQEILERTGVSVEIPPSDSISETVILRGEPEKLGQALTEVYAKANSFTVSSVAAPSWLHRFIIGKKGQNLAKITQQMPKVHIEFTEGEDKITLEGPTEDVNVAQEQIEGMVKDLINRMDYVEINIDHKFHRHLIGKSGANINRIKDQYKVSVRIPPDSEKSNLIRIEGDPQGVQQAKRELLELASRMENERTKDLIIEQRFHRTIIGQKGERIREIRDKFPEVIINFPDPAQKSDIVQLRGPKNEVEKCTKYMQKMVADLVENSYSISVPIFKQFHKNIIGKGGANIKKIREESNTKIDLPAENSNSETIIITGKRANCEAARSRILSIQKDLANIAEVEVSIPAKLHNSLIGTKGRLIRSIMEECGGVHIHFPVEGSGSDTVVIRGPSSDVEKAKKQLLHLAEEKQTKSFTVDIRAKPEYHKFLIGKGGGKIRKVRDSTGARVIFPAAEDKDQDLITIIGKEDAVREAQKELEALIQNLDNVVEDSMLVDPKHHRHFVIRRGQVLREIAEEYGGVMVSFPRSGTQSDKVTLKGAKDCVEAAKKRIQEIIEDLEAQVTLECAIPQKFHRSVMGPKGSRIQQITRDFSVQIKFPDREENAVHSTEPVVQENGDEAGEGREAKDCDPGSPRRCDIIIISGRKEKCEAAKEALEALVPVTIEVEVPFDLHRYVIGQKGSGIRKMMDEFEVNIHVPAPELQSDIIAITGLAANLDRAKAGLLERVKELQAEQEDRALRSFKLSVTVDPKYHPKIIGRKGAVITQIRLEHDVNIQFPDKDDGNQPQDQITITGYEKNTEAARDAILRIVGELEQMVSEDVPLDHRVHARIIGARGKAIRKIMDEFKVDIRFPQSGAPDPNCVTVTGLPENVEEAIDHILNLEEEYLADVVDSEALQVYMKPPAHEEAKAPSRGFVVRDAPWTASSSEKAPDMSSSEEFPSFGAQVAPKTLPWGPKR

PTMs - Q00341 基板として

Site PTM Type Enzyme
S2 Acetylation
T8 Phosphorylation O14757 (CHEK1)
S11 Phosphorylation
K25 Ubiquitination
T28 Phosphorylation
S31 Phosphorylation
S35 Phosphorylation
T39 Phosphorylation
Y40 Phosphorylation
K41 Ubiquitination
K90 Ubiquitination
T111 Phosphorylation
S126 Phosphorylation
K138 Ubiquitination
K159 Ubiquitination
K172 Ubiquitination
K179 Ubiquitination
K197 Ubiquitination
K202 Ubiquitination
S216 Phosphorylation
K221 Ubiquitination
K231 Ubiquitination
Y241 Phosphorylation
T271 Phosphorylation
K274 Ubiquitination
K294 Ubiquitination
T296 Phosphorylation
T297 Phosphorylation
K308 Acetylation
K308 Ubiquitination
K314 Ubiquitination
S317 Phosphorylation
K349 Ubiquitination
Y358 Phosphorylation
K360 Ubiquitination
S363 Phosphorylation
S368 Phosphorylation
K383 Ubiquitination
K389 Ubiquitination
T402 Phosphorylation
Y437 Phosphorylation
K453 Ubiquitination
S454 Phosphorylation
Y465 Phosphorylation
K466 Ubiquitination
S468 Phosphorylation
K477 Ubiquitination
K494 Ubiquitination
K510 Ubiquitination
K526 Ubiquitination
K536 Acetylation
K536 Ubiquitination
K550 Ubiquitination
S581 Phosphorylation
Y582 Phosphorylation
S583 Phosphorylation
K594 Ubiquitination
K599 Ubiquitination
K605 Ubiquitination
S611 Phosphorylation
T613 Phosphorylation
K614 Ubiquitination
S624 Phosphorylation
K632 Methylation
K632 Ubiquitination
S645 Phosphorylation
S659 Phosphorylation
K663 Ubiquitination
S667 Phosphorylation
T671 Phosphorylation
K672 Ubiquitination
K711 Ubiquitination
K713 Ubiquitination
K714 Ubiquitination
K723 Ubiquitination
S727 Phosphorylation
K749 Ubiquitination
S756 Phosphorylation
K769 Ubiquitination
K779 Ubiquitination
K810 Ubiquitination
S840 Phosphorylation
S844 Phosphorylation
K846 Ubiquitination
K883 Ubiquitination
K892 Methylation
S894 Phosphorylation
S904 Phosphorylation
C940 S-Nitrosylation
S944 Phosphorylation
K991 Ubiquitination
S993 Phosphorylation
K1031 Ubiquitination
K1039 Ubiquitination
R1048 Methylation
K1054 Ubiquitination
S1056 Phosphorylation
T1058 Phosphorylation
K1062 Ubiquitination
K1066 Ubiquitination
T1076 Phosphorylation
K1108 Ubiquitination
Y1210 Phosphorylation
S1223 Phosphorylation
R1224 Methylation
S1236 Phosphorylation
S1237 Phosphorylation
K1240 Ubiquitination
S1247 Phosphorylation
S1252 Phosphorylation
T1261 Phosphorylation

研究背景

機能:

Appears to play a role in cell sterol metabolism. It may function to protect cells from over-accumulation of cholesterol.

細胞の位置付け:

Cytoplasm. Nucleus.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location

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