AFfirm™ SPTBN1 Mouse Monoclonal Antibody - #BF8532
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
折りたたみ/展開
Beta G spectrin; Beta II spectrin; Beta spectrin 2; Beta spectrin II; Beta-II spectrin; betaSpII; brain 1; ELF; Embryonic liver beta fodrin; Fodrin beta chain; non-erythroid beta chain 1; Spectrin; Spectrin beta chain; Spectrin, beta, non erythrocytic 1; Spectrin, non erythroid beta chain 1; SPTB2; SPTB2_HUMAN; SPTBN1;
免疫原
- Q01082 SPTB2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MTTTVATDYDNIEIQQQYSDVNNRWDVDDWDNENSSARLFERSRIKALADEREAVQKKTFTKWVNSHLARVSCRITDLYTDLRDGRMLIKLLEVLSGERLPKPTKGRMRIHCLENVDKALQFLKEQRVHLENMGSHDIVDGNHRLTLGLIWTIILRFQIQDISVETEDNKEKKSAKDALLLWCQMKTAGYPNVNIHNFTTSWRDGMAFNALIHKHRPDLIDFDKLKKSNAHYNLQNAFNLAEQHLGLTKLLDPEDISVDHPDEKSIITYVVTYYHYFSKMKALAVEGKRIGKVLDNAIETEKMIEKYESLASDLLEWIEQTIIILNNRKFANSLVGVQQQLQAFNTYRTVEKPPKFTEKGNLEVLLFTIQSKMRANNQKVYMPREGKLISDINKAWERLEKAEHERELALRNELIRQEKLEQLARRFDRKAAMRETWLSENQRLVSQDNFGFDLPAVEAATKKHEAIETDIAAYEERVQAVVAVARELEAENYHDIKRITARKDNVIRLWEYLLELLRARRQRLEMNLGLQKIFQEMLYIMDWMDEMKVLVLSQDYGKHLLGVEDLLQKHTLVEADIGIQAERVRGVNASAQKFATDGEGYKPCDPQVIRDRVAHMEFCYQELCQLAAERRARLEESRRLWKFFWEMAEEEGWIREKEKILSSDDYGKDLTSVMRLLSKHRAFEDEMSGRSGHFEQAIKEGEDMIAEEHFGSEKIRERIIYIREQWANLEQLSAIRKKRLEEASLLHQFQADADDIDAWMLDILKIVSSSDVGHDEYSTQSLVKKHKDVAEEIANYRPTLDTLHEQASALPQEHAESPDVRGRLSGIEERYKEVAELTRLRKQALQDTLALYKMFSEADACELWIDEKEQWLNNMQIPEKLEDLEVIQHRFESLEPEMNNQASRVAVVNQIARQLMHSGHPSEKEIKAQQDKLNTRWSQFRELVDRKKDALLSALSIQNYHLECNETKSWIREKTKVIESTQDLGNDLAGVMALQRKLTGMERDLVAIEAKLSDLQKEAEKLESEHPDQAQAILSRLAEISDVWEEMKTTLKNREASLGEASKLQQFLRDLDDFQSWLSRTQTAIASEDMPNTLTEAEKLLTQHENIKNEIDNYEEDYQKMRDMGEMVTQGQTDAQYMFLRQRLQALDTGWNELHKMWENRQNLLSQSHAYQQFLRDTKQAEAFLNNQEYVLAHTEMPTTLEGAEAAIKKQEDFMTTMDANEEKINAVVETGRRLVSDGNINSDRIQEKVDSIDDRHRKNRETASELLMRLKDNRDLQKFLQDCQELSLWINEKMLTAQDMSYDEARNLHSKWLKHQAFMAELASNKEWLDKIEKEGMQLISEKPETEAVVKEKLTGLHKMWEVLESTTQTKAQRLFDANKAELFTQSCADLDKWLHGLESQIQSDDYGKDLTSVNILLKKQQMLENQMEVRKKEIEELQSQAQALSQEGKSTDEVDSKRLTVQTKFMELLEPLNERKHNLLASKEIHQFNRDVEDEILWVGERMPLATSTDHGHNLQTVQLLIKKNQTLQKEIQGHQPRIDDIFERSQNIVTDSSSLSAEAIRQRLADLKQLWGLLIEETEKRHRRLEEAHRAQQYYFDAAEAEAWMSEQELYMMSEEKAKDEQSAVSMLKKHQILEQAVEDYAETVHQLSKTSRALVADSHPESERISMRQSKVDKLYAGLKDLAEERRGKLDERHRLFQLNREVDDLEQWIAEREVVAGSHELGQDYEHVTMLQERFREFARDTGNIGQERVDTVNHLADELINSGHSDAATIAEWKDGLNEAWADLLELIDTRTQILAASYELHKFYHDAKEIFGRIQDKHKKLPEELGRDQNTVETLQRMHTTFEHDIQALGTQVRQLQEDAARLQAAYAGDKADDIQKRENEVLEAWKSLLDACESRRVRLVDTGDKFRFFSMVRDLMLWMEDVIRQIEAQEKPRDVSSVELLMNNHQGIKAEIDARNDSFTTCIELGKSLLARKHYASEEIKEKLLQLTEKRKEMIDKWEDRWEWLRLILEVHQFSRDASVAEAWLLGQEPYLSSREIGQSVDEVEKLIKRHEAFEKSAATWDERFSALERLTTLELLEVRRQQEEEERKRRPPSPEPSTKVSEEAESQQQWDTSKGEQVSQNGLPAEQGSPRMAETVDTSEMVNGATEQRTSSKESSPIPSPTSDRKAKTALPAQSAATLPARTQETPSAQMEGFLNRKHEWEAHNKKASSRSWHNVYCVINNQEMGFYKDAKTAASGIPYHSEVPVSLKEAVCEVALDYKKKKHVFKLRLNDGNEYLFQAKDDEEMNTWIQAISSAISSDKHEVSASTQSTPASSRAQTLPTSVVTITSESSPGKREKDKEKDKEKRFSLFGKKK
PTMs - Q01082 基板として
Site | PTM Type | Enzyme | Source |
---|---|---|---|
T2 | Acetylation | Uniprot | |
Y9 | Phosphorylation | Uniprot | |
Y18 | Phosphorylation | Uniprot | |
K62 | Ubiquitination | Uniprot | |
Y79 | Phosphorylation | Uniprot | |
T80 | Phosphorylation | Uniprot | |
K90 | Acetylation | Uniprot | |
S96 | Phosphorylation | Uniprot | |
K105 | Ubiquitination | Uniprot | |
K118 | Acetylation | Uniprot | |
K118 | Ubiquitination | Uniprot | |
K124 | Acetylation | Uniprot | |
K124 | Ubiquitination | Uniprot | |
S163 | Phosphorylation | Uniprot | |
K214 | Sumoylation | Uniprot | |
K214 | Ubiquitination | Uniprot | |
K224 | Ubiquitination | Uniprot | |
K227 | Ubiquitination | Uniprot | |
S228 | Phosphorylation | Uniprot | |
K249 | Ubiquitination | Uniprot | |
S257 | Phosphorylation | Uniprot | |
Y274 | Phosphorylation | Uniprot | |
S278 | Phosphorylation | Uniprot | |
K288 | Ubiquitination | Uniprot | |
K292 | Ubiquitination | Uniprot | |
S333 | Phosphorylation | Uniprot | |
K359 | Ubiquitination | Uniprot | |
Y381 | Phosphorylation | Uniprot | |
K387 | Ubiquitination | Uniprot | |
K419 | Ubiquitination | Uniprot | |
K462 | Ubiquitination | Uniprot | |
K463 | Ubiquitination | Uniprot | |
T469 | Phosphorylation | Uniprot | |
Y474 | Phosphorylation | Uniprot | |
Y493 | Phosphorylation | Uniprot | |
K497 | Acetylation | Uniprot | |
K497 | Ubiquitination | Uniprot | |
K558 | Ubiquitination | Uniprot | |
K593 | Ubiquitination | Uniprot | |
K602 | Ubiquitination | Uniprot | |
Y620 | Phosphorylation | Uniprot | |
K659 | Ubiquitination | Uniprot | |
S662 | Phosphorylation | Uniprot | |
Y666 | Phosphorylation | Uniprot | |
K668 | Ubiquitination | Uniprot | |
R681 | Methylation | Uniprot | |
K714 | Ubiquitination | Uniprot | |
Y721 | Phosphorylation | Uniprot | |
S770 | Phosphorylation | Uniprot | |
Y777 | Phosphorylation | Uniprot | |
S778 | Phosphorylation | Uniprot | |
T779 | Phosphorylation | Uniprot | |
S781 | Phosphorylation | Uniprot | |
K784 | Ubiquitination | Uniprot | |
Y796 | Phosphorylation | Uniprot | |
S817 | Phosphorylation | Uniprot | |
S825 | Phosphorylation | Uniprot | |
Y831 | Phosphorylation | Uniprot | |
K832 | Ubiquitination | Uniprot | |
T838 | Phosphorylation | Uniprot | |
K842 | Ubiquitination | Uniprot | |
S856 | Phosphorylation | Uniprot | |
K924 | Acetylation | Uniprot | |
K924 | Ubiquitination | Uniprot | |
S938 | Phosphorylation | Uniprot | |
K976 | Ubiquitination | Uniprot | |
K997 | Ubiquitination | Uniprot | |
T999 | Phosphorylation | Uniprot | |
K1011 | Ubiquitination | Uniprot | |
S1013 | Phosphorylation | Uniprot | |
K1021 | Ubiquitination | Uniprot | |
S1041 | Phosphorylation | Uniprot | |
T1049 | Phosphorylation | Uniprot | |
S1057 | Phosphorylation | Uniprot | |
S1076 | Phosphorylation | Uniprot | |
S1079 | Phosphorylation | Uniprot | |
T1095 | Phosphorylation | Uniprot | |
K1099 | Ubiquitination | Uniprot | |
K1108 | Ubiquitination | Uniprot | |
Y1114 | Phosphorylation | Uniprot | |
Y1118 | Phosphorylation | Uniprot | |
Y1137 | Phosphorylation | Uniprot | |
S1168 | Phosphorylation | Uniprot | |
Y1171 | Phosphorylation | Uniprot | |
K1209 | Ubiquitination | Uniprot | |
T1216 | Phosphorylation | Uniprot | |
T1217 | Phosphorylation | Uniprot | |
R1233 | Methylation | Uniprot | |
S1237 | Phosphorylation | Uniprot | |
S1243 | Phosphorylation | Uniprot | |
R1245 | Methylation | Uniprot | |
K1249 | Ubiquitination | Uniprot | |
K1259 | Sumoylation | Uniprot | |
T1263 | Phosphorylation | Uniprot | |
K1272 | Sumoylation | Uniprot | |
S1302 | Phosphorylation | Uniprot | |
Y1303 | Phosphorylation | Uniprot | |
K1335 | Ubiquitination | Uniprot | |
K1360 | Ubiquitination | Uniprot | |
K1372 | Ubiquitination | Uniprot | |
K1381 | Ubiquitination | Uniprot | |
S1388 | Phosphorylation | Uniprot | |
K1394 | Ubiquitination | Uniprot | |
S1401 | Phosphorylation | Uniprot | |
S1405 | Phosphorylation | Uniprot | |
K1421 | Ubiquitination | Uniprot | |
K1434 | Ubiquitination | Uniprot | |
S1447 | Phosphorylation | Uniprot | |
K1451 | Ubiquitination | Uniprot | |
T1462 | Phosphorylation | Uniprot | |
K1478 | Ubiquitination | Uniprot | |
K1485 | Acetylation | Uniprot | |
K1485 | Ubiquitination | Uniprot | |
K1532 | Ubiquitination | Uniprot | |
S1557 | Phosphorylation | Uniprot | |
S1559 | Phosphorylation | Uniprot | |
K1571 | Ubiquitination | Uniprot | |
K1633 | Ubiquitination | Uniprot | |
Y1644 | Phosphorylation | Uniprot | |
T1647 | Phosphorylation | Uniprot | |
K1653 | Acetylation | Uniprot | |
K1653 | Ubiquitination | Uniprot | |
S1666 | Phosphorylation | Uniprot | |
S1670 | Phosphorylation | Uniprot | |
K1678 | Ubiquitination | Uniprot | |
Y1680 | Phosphorylation | Uniprot | |
K1684 | Ubiquitination | Uniprot | |
Y1730 | Phosphorylation | Uniprot | |
T1734 | Phosphorylation | Uniprot | |
S1804 | Phosphorylation | Uniprot | |
Y1805 | Phosphorylation | Uniprot | |
K1809 | Acetylation | Uniprot | |
Y1811 | Phosphorylation | Uniprot | |
K1815 | Acetylation | Uniprot | |
K1815 | Ubiquitination | Uniprot | |
K1878 | Ubiquitination | Uniprot | |
S1902 | Phosphorylation | Uniprot | |
K1913 | Acetylation | Uniprot | |
S1966 | Phosphorylation | Uniprot | |
Y1983 | Phosphorylation | Uniprot | |
S1985 | Phosphorylation | Uniprot | |
K1989 | Acetylation | Uniprot | |
K1991 | Ubiquitination | Uniprot | |
T1996 | Phosphorylation | Uniprot | |
Y2039 | Phosphorylation | Uniprot | |
S2041 | Phosphorylation | Uniprot | |
S2042 | Phosphorylation | Uniprot | |
S2048 | Phosphorylation | Uniprot | |
K2064 | Ubiquitination | Uniprot | |
R2072 | Methylation | Uniprot | |
T2080 | Phosphorylation | Uniprot | |
T2081 | Phosphorylation | Uniprot | |
S2102 | Phosphorylation | Uniprot | |
S2106 | Phosphorylation | Uniprot | |
T2107 | Phosphorylation | Uniprot | |
S2110 | Phosphorylation | P68400 (CSNK2A1) | Uniprot |
S2115 | Phosphorylation | Uniprot | |
T2121 | Phosphorylation | Uniprot | |
K2123 | Ubiquitination | Uniprot | |
S2128 | Phosphorylation | Uniprot | |
S2138 | Phosphorylation | Uniprot | |
T2147 | Phosphorylation | Uniprot | |
S2148 | Phosphorylation | Uniprot | |
T2155 | Phosphorylation | Uniprot | |
T2159 | Phosphorylation | P17612 (PRKACA) , P68400 (CSNK2A1) | Uniprot |
S2160 | Phosphorylation | Uniprot | |
S2161 | Phosphorylation | Uniprot | |
S2164 | Phosphorylation | Uniprot | |
S2165 | Phosphorylation | Uniprot | |
S2169 | Phosphorylation | Uniprot | |
T2171 | Phosphorylation | Uniprot | |
S2172 | Phosphorylation | Uniprot | |
K2177 | Ubiquitination | Uniprot | |
S2184 | Phosphorylation | Uniprot | |
T2187 | Phosphorylation | Uniprot | |
T2195 | Phosphorylation | Uniprot | |
K2207 | Ubiquitination | Uniprot | |
S2221 | Phosphorylation | Uniprot | |
K2241 | Ubiquitination | Uniprot | |
Y2249 | Phosphorylation | Uniprot | |
S2251 | Phosphorylation | Uniprot | |
Y2268 | Phosphorylation | Uniprot | |
K2269 | Acetylation | Uniprot | |
K2270 | Acetylation | Uniprot | |
K2276 | Ubiquitination | Uniprot | |
Y2285 | Phosphorylation | Uniprot | |
T2297 | Phosphorylation | Uniprot | |
K2310 | Ubiquitination | Uniprot | |
S2314 | Phosphorylation | Uniprot | |
S2316 | Phosphorylation | Uniprot | |
T2317 | Phosphorylation | Uniprot | |
S2319 | Phosphorylation | Uniprot | |
T2320 | Phosphorylation | Uniprot | |
S2323 | Phosphorylation | Uniprot | |
S2324 | O-Glycosylation | Uniprot | |
S2324 | Phosphorylation | Uniprot | |
T2328 | Phosphorylation | Uniprot | |
T2331 | Phosphorylation | Uniprot | |
S2332 | Phosphorylation | Uniprot | |
T2335 | Phosphorylation | Uniprot | |
T2337 | Phosphorylation | Uniprot | |
S2338 | Phosphorylation | Uniprot | |
S2340 | Phosphorylation | Uniprot | |
S2341 | Phosphorylation | Uniprot | |
K2344 | Acetylation | Uniprot | |
K2344 | Ubiquitination | Uniprot | |
S2358 | Phosphorylation | Uniprot | |
K2362 | Acetylation | Uniprot | |
K2363 | Acetylation | Uniprot |
研究背景
Fodrin, which seems to be involved in secretion, interacts with calmodulin in a calcium-dependent manner and is thus candidate for the calcium-dependent movement of the cytoskeleton at the membrane.
Cytoplasm>Cytoskeleton. Cytoplasm>Myofibril>Sarcomere>M line.
Note: Colocalizes with ANK2 in a distinct intracellular compartment of neonatal cardiomyocytes.
Cell membrane>Peripheral membrane protein>Cytoplasmic side.
Isoform 2 is present in brain, lung and kidney (at protein level).
Interacts with CAMSAP1. Interacts with ANK2. Interacts with CPNE4 (via VWFA domain) (By similarity). Like erythrocyte spectrin, the spectrin-like proteins are capable to form dimers which can further associate to tetramers (By similarity). Isoform Short cannot bind to the axonal protein fodaxin.
Belongs to the spectrin family.
Restrictive clause
Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.
For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.