AFfirm™ PPP1R7 Mouse Monoclonal Antibody - #BF8538

(2)  
製品: PPP1R7 Mouse Monoclonal Antibody
カタログ: BF8538
タンパク質の説明: Mouse monoclonal antibody to PPP1R7
アプリケーション: WB IHC
反応性: Human, Rat
予測: Pig, Bovine, Rabbit
分子量: 48 KD; 42kD(Calculated).
ユニプロット: Q15435

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MSDS
説明書
COA
プロトコル
WB Handbook
IHC Protocol
IF/ICC Protocol

製品説明

ソース:
Mouse
アプリケーション:
WB 1:500-1:3000, IHC 1:50-1:200
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Rat
クローナリティ:
Monoclonal [AFfirm8538]
コンジュゲート:
Unconjugated.
精製:
Affinity-chromatography.
保存:
Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ／展開

MGC105784; PP1R7_HUMAN; PPP1R7; protein phosphatase 1 regulatory (inhibitor) subunit 7; Protein phosphatase 1 regulatory subunit 22; Protein phosphatase 1 regulatory subunit 7 alpha2; Protein phosphatase 1 regulatory subunit 7; Protein phosphatase 1 regulatory subunit 7 beta1; Protein phosphatase 1 regulatory subunit 7 beta2; SDS 22; SDS22;

免疫原

免疫原:
Uniprot:

Q15435(PP1R7_HUMAN) >>Visit HPA database.

遺伝子(ID):
PPP1R7(5510)
発現特異性:
Q15435 PP1R7_HUMAN:

Widely expressed.

タンパク質配列:
MAAERGAGQQQSQEMMEVDRRVESEESGDEEGKKHSSGIVADLSEQSLKDGEERGEEDPEEEHELPVDMETINLDRDAEDVDLNHYRIGKIEGFEVLKKVKTLCLRQNLIKCIENLEELQSLRELDLYDNQIKKIENLEALTELEILDISFNLLRNIEGVDKLTRLKKLFLVNNKISKIENLSNLHQLQMLELGSNRIRAIENIDTLTNLESLFLGKNKITKLQNLDALTNLTVLSMQSNRLTKIEGLQNLVNLRELYLSHNGIEVIEGLENNNKLTMLDIASNRIKKIENISHLTELQEFWMNDNLLESWSDLDELKGARSLETVYLERNPLQKDPQYRRKVMLALPSVRQIDATFVRF

PTMs - Q15435 基板として

Site PTM Type Enzyme
A2 Acetylation
S12 Phosphorylation
S24 Phosphorylation
S27 Phosphorylation
K34 Acetylation
S36 Phosphorylation
S37 Phosphorylation
S44 Phosphorylation
S47 Phosphorylation
K49 Ubiquitination
R54 Methylation
R76 Methylation
K90 Ubiquitination
K98 Ubiquitination
K101 Ubiquitination
K111 Ubiquitination
K133 Ubiquitination
K162 Ubiquitination
K167 Ubiquitination
K168 Ubiquitination
K175 Ubiquitination
K178 Ubiquitination
K217 Ubiquitination
K219 Ubiquitination
K222 Ubiquitination
T243 Phosphorylation
K244 Ubiquitination
T277 Phosphorylation
S322 Phosphorylation
Y327 Phosphorylation
K335 Ubiquitination

研究背景

機能:

Regulatory subunit of protein phosphatase 1.

細胞の位置付け:

Nucleus.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Widely expressed.

サブユニット構造:

Interacts with PPP1CA, PPP1CB and PPP1CC/PPP1G isoform 1.

タンパク質ファミリー:

Belongs to the SDS22 family.

Restrictive clause

 

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