製品: RHPN1 Mouse Monoclonal Antibody
カタログ: BF8545
タンパク質の説明: Mouse monoclonal antibody to RHPN1
アプリケーション: WB
反応性: Human
分子量: 70,100kD; 74kD(Calculated).
ユニプロット: Q8TCX5

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製品説明

ソース:
Mouse
アプリケーション:
WB 1:500-1:3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human
クローナリティ:
Monoclonal [AFfirm8545]
コンジュゲート:
Unconjugated.
精製:
Affinity-chromatography.
保存:
Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

GTP Rho binding protein 1; GTP-Rho-binding protein 1; ODF5; Outer dense fiber of sperm tails 5; Rhophilin 1; Rhophilin-1; RHPN; Rhpn1; RHPN1_HUMAN;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
タンパク質配列:
MILEERPDGAGAGEESPRLQGCDSLTQIQCGQLQSRRAQIHQQIDKELQMRTGAENLYRATSNNRVRETVALELSYVNSNLQLLKEELEELSGGVDPGRHGSEAVTVPMIPLGLKETKELDWSTPLKELISVHFGEDGASYEAEIRELEALRQAMRTPSRNESGLELLTAYYNQLCFLDARFLTPARSLGLFFHWYDSLTGVPAQQRALAFEKGSVLFNIGALHTQIGARQDRSCTEGARRAMEAFQRAAGAFSLLRENFSHAPSPDMSAASLCALEQLMMAQAQECVFEGLSPPASMAPQDCLAQLRLAQEAAQVAAEYRLVHRTMAQPPVHDYVPVSWTALVHVKAEYFRSLAHYHVAMALCDGSPATEGELPTHEQVFLQPPTSSKPRGPVLPQELEERRQLGKAHLKRAILGQEEALRLHALCRVLREVDLLRAVISQTLQRSLAKYAELDREDDFCEAAEAPDIQPKTHQKPEARMPRLSQGKGPDIFHRLGPLSVFSAKNRWRLVGPVHLTRGEGGFGLTLRGDSPVLIAAVIPGSQAAAAGLKEGDYIVSVNGQPCRWWRHAEVVTELKAAGEAGASLQVVSLLPSSRLPSLGDRRPVLLGPRGLLRSQREHGCKTPASTWASPRPLLNWSRKAQQGKTGGCPQPCAPVKPAPPSSLKHPGWP

PTMs - Q8TCX5 基板として

Site PTM Type Enzyme
S16 Phosphorylation
S24 Phosphorylation
T26 Phosphorylation
S92 Phosphorylation
K118 Ubiquitination
T157 Phosphorylation
S159 Phosphorylation
S163 Phosphorylation
S188 Phosphorylation
K411 Acetylation
K450 Ubiquitination
K505 Ubiquitination
R632 Methylation

研究背景

機能:

Has no enzymatic activity. May serve as a target for Rho, and interact with some cytoskeletal component upon Rho binding or relay a Rho signal to other molecules.

サブユニット構造:

Binds specifically to GTP-Rho. Interacts with ROPN1.

タンパク質ファミリー:

The PDZ domain mediates interaction with ROPN1.

Belongs to the RHPN family.

Restrictive clause

 

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