AFfirm™ NAA40 Mouse Monoclonal Antibody - #BF8579
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
折りたたみ／展開
N acetyltransferase 11 (GCN5 related, putative); N alpha acetyl transferase 40; N alpha acetyltransferase 40; N(alpha) acetyltransferase 40; N(alpha) acetyltransferase 40, NatD catalytic subunit, homolog; N(alpha)-acetyltransferase 40, NatD catalytic subunit, homolog (S. cerevisiae); N-acetyltransferase 11; N-alpha-acetyltransferase 40, NatD catalytic subunit; naa40; NAA40_HUMAN; NAT11; NatD catalytic subunit; PATT1;
免疫原
A synthesized peptide derived from Human NAA40.
Widely expressed; with the highest expression level in liver and the lowest expression in brain (at protein level).
- Q86UY6 NAA40_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MGRKSSKAKEKKQKRLEERAAMDAVCAKVDAANRLGDPLEAFPVFKKYDRNGLNVSIECKRVSGLEPATVDWAFDLTKTNMQTMYEQSEWGWKDREKREEMTDDRAWYLIAWENSSVPVAFSHFRFDVECGDEVLYCYEVQLESKVRRKGLGKFLIQILQLMANSTQMKKVMLTVFKHNHGAYQFFREALQFEIDDSSPSMSGCCGEDCSYEILSRRTKFGDSHHSHAGGHCGGCCH
研究背景
N-alpha-acetyltransferase that specifically mediates the acetylation of the N-terminal residues of histones H4 and H2A. In contrast to other N-alpha-acetyltransferase, has a very specific selectivity for histones H4 and H2A N-terminus and specifically recognizes the 'Ser-Gly-Arg-Gly sequence'. Acts as a negative regulator of apoptosis. May play a role in hepatic lipid metabolism (By similarity).
Cytoplasm. Nucleus.
Widely expressed; with the highest expression level in liver and the lowest expression in brain (at protein level).
Belongs to the acetyltransferase family. NAA40 subfamily.
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