AFfirm™ SMAP2 Mouse Monoclonal Antibody - #BF8585

製品: SMAP2 Mouse Monoclonal Antibody
カタログ: BF8585
タンパク質の説明: Mouse monoclonal antibody to SMAP2
アプリケーション: WB
反応性: Human
分子量: 47kD; 47kD(Calculated).
ユニプロット: Q8WU79

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MS Report
HPLC Report
MSDS
説明書
COA
プロトコル
WB Handbook
IHC Protocol
IF/ICC Protocol

製品説明

ソース:
Mouse
アプリケーション:
WB 1:500-1:3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human
クローナリティ:
Monoclonal [AFfirm8585]
コンジュゲート:
Unconjugated.
精製:
Affinity-chromatography.
保存:
Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ／展開

RP1-228H13.3; Small ArfGAP2; SMAP 1L; Smap2; SMAP2_HUMAN; Stromal membrane associated GTPase activating protein 2; Stromal membrane-associated protein 1-like; Stromal membrane-associated protein 2;

免疫原

免疫原:

A synthesized peptide derived from Human SMAP2.

Uniprot:

Q8WU79(SMAP2_HUMAN) >>Visit HPA database.

遺伝子(ID):
SMAP2(64744)
タンパク質配列:
MTGKSVKDVDRYQAVLANLLLEEDNKFCADCQSKGPRWASWNIGVFICIRCAGIHRNLGVHISRVKSVNLDQWTQEQIQCMQEMGNGKANRLYEAYLPETFRRPQIDPAVEGFIRDKYEKKKYMDRSLDINAFRKEKDDKWKRGSEPVPEKKLEPVVFEKVKMPQKKEDPQLPRKSSPKSTAPVMDLLGLDAPVACSIANSKTSNTLEKDLDLLASVPSPSSSGSRKVVGSMPTAGSAGSVPENLNLFPEPGSKSEEIGKKQLSKDSILSLYGSQTPQMPTQAMFMAPAQMAYPTAYPSFPGVTPPNSIMGSMMPPPVGMVAQPGASGMVAPMAMPAGYMGGMQASMMGVPNGMMTTQQAGYMAGMAAMPQTVYGVQPAQQLQWNLTQMTQQMAGMNFYGANGMMNYGQSMSGGNGQAANQTLSPQMWK

研究背景

機能:

GTPase activating protein that acts on ARF1. Can also activate ARF6 (in vitro). May play a role in clathrin-dependent retrograde transport from early endosomes to the trans-Golgi network (By similarity).

細胞の位置付け:

Cytoplasm.
Note: Detected in multiple foci throughout the cytoplasm and in juxtanuclear structures.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
サブユニット構造:

Interacts with ARF1. Interacts with PICALM and clathrin heavy chains (By similarity).

研究領域

· Cellular Processes > Transport and catabolism > Endocytosis.   (View pathway)

Restrictive clause

 

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