AFfirm™ CEP27 Mouse Monoclonal Antibody - #BF8644
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
折りたたみ／展開
C15orf25; Centrosomal protein 27 kDa; Centrosomal protein of 27 kDa; CEP27; Chromosome 15 open reading frame 25; FLJ10460; HAUS augmin-like complex subunit 2; Haus2; HAUS2_HUMAN; HsT17025;
免疫原
- Q9NVX0 HAUS2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAAANPWDPASAPNGAGLVLGHFIASGMVNQEMLNMSKKTVSCFVNFTRLQQITNIQAEIYQKNLEIELLKLEKDTADVVHPFFLAQKCHTLQSMNNHLEAVLKEKRSLRQRLLKPMCQENLPIEAVYHRYMVHLLELAVTFIERLETHLETIRNIPHLAANLKKMNQALAKMDILVTETEELAENILKWRKQQNEVSSCIPKILAEESYLYKHDIIMPPLPFTSKVHVQTINAK
PTMs - Q9NVX0 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S37 | Phosphorylation | Uniprot | |
| K39 | Ubiquitination | Uniprot | |
| K63 | Ubiquitination | Uniprot | |
| K71 | Ubiquitination | Uniprot | |
| K74 | Ubiquitination | Uniprot | |
| K88 | Ubiquitination | Uniprot | |
| K104 | Ubiquitination | Uniprot | |
| K115 | Ubiquitination | Uniprot | |
| K192 | Ubiquitination | Uniprot | |
| K203 | Ubiquitination | Uniprot | |
| Y210 | Phosphorylation | Uniprot | |
| K213 | Ubiquitination | Uniprot | |
| K226 | Ubiquitination | Uniprot |
研究背景
Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex.
Cytoplasm>Cytoskeleton>Microtubule organizing center>Centrosome. Cytoplasm>Cytoskeleton>Spindle.
Note: Localizes to interphase centrosomes and to mitotic spindle microtubules.
Component of the HAUS augmin-like complex. The complex interacts with the gamma-tubulin ring complex and this interaction is required for spindle assembly.
Belongs to the HAUS2 family.
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