AFfirm™ F13B Mouse Monoclonal Antibody - #BF8645
製品説明
ソース:
Mouse
アプリケーション:
WB 1:500-1:3000
*The optimal dilutions should be determined by the end user.
*Tips:
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
反応性:
Human
クローナリティ:
Monoclonal [AFfirm8645]
特異性:
F13B Mouse Monoclonal Antibody detects endogenous levels of total F13B.
コンジュゲート:
Unconjugated.
精製:
Affinity-chromatography.
保存:
Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:
折りたたみ／展開
Coagulation factor XIII, A2 polypeptide; Coagulation factor XIII, B polypeptide; F13A2; F13B; FXIIIB;
免疫原
免疫原:
Uniprot:
遺伝子(ID):
タンパク質配列:
- P05160 F13B_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MRLKNLTFIIILIISGELYAEEKPCGFPHVENGRIAQYYYTFKSFYFPMSIDKKLSFFCLAGYTTESGRQEEQTTCTTEGWSPEPRCFKKCTKPDLSNGYISDVKLLYKIQENMRYGCASGYKTTGGKDEEVVQCLSDGWSSQPTCRKEHETCLAPELYNGNYSTTQKTFKVKDKVQYECATGYYTAGGKKTEEVECLTYGWSLTPKCTKLKCSSLRLIENGYFHPVKQTYEEGDVVQFFCHENYYLSGSDLIQCYNFGWYPESPVCEGRRNRCPPPPLPINSKIQTHSTTYRHGEIVHIECELNFEIHGSAEIRCEDGKWTEPPKCIEGQEKVACEEPPFIENGAANLHSKIYYNGDKVTYACKSGYLLHGSNEITCNRGKWTLPPECVENNENCKHPPVVMNGAVADGILASYATGSSVEYRCNEYYLLRGSKISRCEQGKWSSPPVCLEPCTVNVDYMNRNNIEMKWKYEGKVLHGDLIDFVCKQGYDLSPLTPLSELSVQCNRGEVKYPLCTRKESKGMCTSPPLIKHGVIISSTVDTYENGSSVEYRCFDHHFLEGSREAYCLDGMWTTPPLCLEPCTLSFTEMEKNNLLLKWDFDNRPHILHGEYIEFICRGDTYPAELYITGSILRMQCDRGQLKYPRCIPRQSTLSYQEPLRT
PTMs - P05160 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| N162 | N-Glycosylation | Uniprot | |
| T182 | Phosphorylation | Uniprot | |
| S373 | Phosphorylation | Uniprot | |
| Y512 | Phosphorylation | Uniprot | |
| N545 | N-Glycosylation | Uniprot | |
| Y643 | Phosphorylation | Uniprot | |
| T661 | Phosphorylation | Uniprot |
研究背景
機能:
The B chain of factor XIII is not catalytically active, but is thought to stabilize the A subunits and regulate the rate of transglutaminase formation by thrombin.
細胞の位置付け:
Secreted.
サブユニット構造:
Tetramer of two A chains (F13A1) and two B (F13B) chains.
研究領域
· Organismal Systems > Immune system > Complement and coagulation cascades. (View pathway)
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