製品: SERC1 Mouse Monoclonal Antibody
カタログ: BF8654
タンパク質の説明: Mouse monoclonal antibody to SERC1
アプリケーション: WB
反応性: Human
予測: Mouse, Rat
分子量: 48kDa; 50kD(Calculated).
ユニプロット: Q9NRX5

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製品説明

ソース:
Mouse
アプリケーション:
WB 1:500-1:3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human
クローナリティ:
Monoclonal [AFfirm8654]
特異性:
SERC1 Mouse Monoclonal Antibody detects endogenous levels of total SERC1.
コンジュゲート:
Unconjugated.
精製:
Affinity-chromatography.
保存:
Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

1500011D18Rik; AI315070; AIGP 2; KIAA1253; LRRGT00191; mKIAA1253; SERC1_HUMAN; SERINC1; Serine incorporator 1; TDE1L; TDE2; TMS 2; Tms2; Tumor differentially expressed 1 protein like; Tumor differentially expressed protein 1-like; Tumor differentially expressed protein 2; UNQ396/PRO732;

免疫原

免疫原:

A synthesized peptide derived from human SERC1, corresponding to a region within C-terminal amino acids.

Uniprot:
遺伝子(ID):
タンパク質の説明:
SERINC1 Enhances the incorporation of serine into phosphatidylserine and sphingolipids. Belongs to the TDE1 family. Interacts with SPTLC1.
タンパク質配列:
MGSVLGLCSMASWIPCLCGSAPCLLCRCCPSGNNSTVTRLIYALFLLVGVCVACVMLIPGMEEQLNKIPGFCENEKGVVPCNILVGYKAVYRLCFGLAMFYLLLSLLMIKVKSSSDPRAAVHNGFWFFKFAAAIAIIIGAFFIPEGTFTTVWFYVGMAGAFCFILIQLVLLIDFAHSWNESWVEKMEEGNSRCWYAALLSATALNYLLSLVAIVLFFVYYTHPASCSENKAFISVNMLLCVGASVMSILPKIQESQPRSGLLQSSVITVYTMYLTWSAMTNEPETNCNPSLLSIIGYNTTSTVPKEGQSVQWWHAQGIIGLILFLLCVFYSSIRTSNNSQVNKLTLTSDESTLIEDGGARSDGSLEDGDDVHRAVDNERDGVTYSYSFFHFMLFLASLYIMMTLTNWYRYEPSREMKSQWTAVWVKISSSWIGIVLYVWTLVAPLVLTNRDFD

PTMs - Q9NRX5 基板として

Site PTM Type Enzyme
G2 Myristoylation
S31 Phosphorylation
S35 Phosphorylation
T36 Phosphorylation
T38 Phosphorylation
N298 N-Glycosylation
K343 Ubiquitination
T345 Phosphorylation
T347 Phosphorylation
S348 Phosphorylation
S351 Phosphorylation
T352 Phosphorylation
S361 Phosphorylation
S364 Phosphorylation
Y410 Phosphorylation
S413 Phosphorylation
S418 Phosphorylation
T421 Phosphorylation

研究背景

機能:

Enhances the incorporation of serine into phosphatidylserine and sphingolipids.

細胞の位置付け:

Endoplasmic reticulum membrane>Multi-pass membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
サブユニット構造:

Interacts with SPTLC1.

タンパク質ファミリー:

Belongs to the TDE1 family.

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