AFfirm™ MOGAT2 Mouse Monoclonal Antibody - #BF8702

製品: MOGAT2 Mouse Monoclonal Antibody
カタログ: BF8702
タンパク質の説明: Mouse monoclonal antibody to MOGAT2
アプリケーション: WB
反応性: Human
予測: Human
分子量: 38kD(Calculated).
ユニプロット: Q3SYC2

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関連ダウンロード
MS Report
HPLC Report
MSDS
説明書
COA
プロトコル
WB Handbook
IHC Protocol
IF/ICC Protocol

製品説明

ソース:
Mouse
アプリケーション:
WB 1:500-1:3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human
クローナリティ:
Monoclonal [AFfirm8702]
特異性:
MOGAT2 Mouse Monoclonal Antibody detects endogenous levels of MOGAT2.
コンジュゲート:
Unconjugated.
精製:
Affinity-chromatography.
保存:
Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ／展開

2 acylglycerol O acyltransferase 2; 2-acylglycerol O-acyltransferase 2; Acyl CoA:monoacylglycerol acyltransferase 2; Acyl-CoA:monoacylglycerol acyltransferase 2; DC5; DGAT2L5; Diacylglycerol acyltransferase 2 like protein 5; Diacylglycerol acyltransferase 2-like protein 5; Diacylglycerol O acyltransferase candidate 5; Diacylglycerol O-acyltransferase candidate 5; EC 2.3.1.22; FLJ22644; hDC5; hMGAT2; Mgat1l; MGAT2; MGC119183; MGC119184; MGC119185; MGC189143; mogat2; MOGT2_HUMAN; Monoacylglycerol O acyltransferase 1 like; Monoacylglycerol O acyltransferase 2; Monoacylglycerol O-acyltransferase 2;

免疫原

免疫原:

A synthesized peptide derived from human MOGAT2.

Uniprot:

Q3SYC2(MOGT2_HUMAN) >>Visit HPA database.

遺伝子(ID):
MOGAT2(80168)
発現特異性:
Q3SYC2 MOGT2_HUMAN:

Highly expressed in liver, small intestine, colon, stomach and kidney.

タンパク質配列:
MVEFAPLFMPWERRLQTLAVLQFVFSFLALAEICTVGFIALLFTRFWLLTVLYAAWWYLDRDKPRQGGRHIQAIRCWTIWKYMKDYFPISLVKTAELDPSRNYIAGFHPHGVLAVGAFANLCTESTGFSSIFPGIRPHLMMLTLWFRAPFFRDYIMSAGLVTSEKESAAHILNRKGGGNLLGIIVGGAQEALDARPGSFTLLLRNRKGFVRLALTHGAPLVPIFSFGENDLFDQIPNSSGSWLRYIQNRLQKIMGISLPLFHGRGVFQYSFGLIPYRRPITTVVGKPIEVQKTLHPSEEEVNQLHQRYIKELCNLFEAHKLKFNIPADQHLEFC

研究背景

機能:

Catalyzes the formation of diacylglycerol from 2-monoacylglycerol and fatty acyl-CoA. Has a preference toward monoacylglycerols containing unsaturated fatty acids in an order of C18:3 > C18:2 > C18:1 > C18:0. Plays a central role in absorption of dietary fat in the small intestine by catalyzing the resynthesis of triacylglycerol in enterocytes. May play a role in diet-induced obesity.

細胞の位置付け:

Endoplasmic reticulum membrane>Multi-pass membrane protein. Cytoplasm>Perinuclear region.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Highly expressed in liver, small intestine, colon, stomach and kidney.

タンパク質ファミリー:

Belongs to the diacylglycerol acyltransferase family.

研究領域

· Metabolism > Lipid metabolism > Glycerolipid metabolism.

· Organismal Systems > Digestive system > Fat digestion and absorption.

Restrictive clause

 

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