AFfirm™ DRC3 Mouse Monoclonal Antibody - #BF8715

製品: DRC3 Mouse Monoclonal Antibody
カタログ: BF8715
タンパク質の説明: Mouse monoclonal antibody to DRC3
アプリケーション: WB
反応性: Human
予測: Mouse, Rat
分子量: 60kD; 61kD(Calculated).
ユニプロット: Q9H069

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関連ダウンロード
MS Report
HPLC Report
MSDS
説明書
COA
プロトコル
WB Handbook
IHC Protocol
IF/ICC Protocol

製品説明

ソース:
Mouse
アプリケーション:
WB 1:500-1:3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human
クローナリティ:
Monoclonal [AFfirm8715]
特異性:
DRC3 Mouse Monoclonal Antibody detects endogenous levels of DRC3.
コンジュゲート:
Unconjugated.
精製:
Affinity-chromatography.
保存:
Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ／展開

CFAP134; DRC3; Dynein regulatory complex subunit 3; Leucine rich repeat containing 48; Leucine-rich repeat-containing protein 48; LRC48_HUMAN; LRRC48; RP23 135F6.3;

免疫原

免疫原:

A synthesized peptide derived from human DRC3.

Uniprot:

Q9H069(DRC3_HUMAN) >>Visit HPA database.

遺伝子(ID):
DRC3(83450)
タンパク質配列:
MNQPCNSMEPRVMDDDMLKLAVGDQGPQEEAGQLAKQEGILFKDVLSLQLDFRNILRIDNLWQFENLRKLQLDNNIIEKIEGLENLAHLVWLDLSFNNIETIEGLDTLVNLEDLSLFNNRISKIDSLDALVKLQVLSLGNNRIDNMMNIIYLRRFKCLRTLSLSRNPISEAEDYKMFICAYLPDLMYLDYRRIDDHTKKLAEAKHQYSIDELKHQENLMQAQLEDEQAQREELEKHKTAFVEHLNGSFLFDSMYAEDSEGNNLSYLPGVGELLETYKDKFVIICVNIFEYGLKQQEKRKTELDTFSECVREAIQENQEQGKRKIAKFEEKHLSSLSAIREELELPNIEKMILECSADISELFDALMTLEMQLVEQLEETINMFERNIVDMVGLFIENVQSLMAQCRDLENHHHEKLLEISISTLEKIVEGDLDEDLPNDLRALFVDKDTIVNAVGASHDIHLLKIDNREDELVTRINSWCTRLIDRIHKDEIMRNRKRVKEINQYIDHMQSELDNLECGDILD

研究背景

機能:

Component of the nexin-dynein regulatory complex (N-DRC) a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes.

細胞の位置付け:

Cytoplasm>Cytoskeleton>Cilium axoneme. Cell projection>Cilium. Cytoplasm>Cytoskeleton>Flagellum axoneme.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
サブユニット構造:

Component of the nexin-dynein regulatory complex (N-DRC). Interacts with TCTE1/DRC5.

タンパク質ファミリー:

Belongs to the DRC3 family.

Restrictive clause

 

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