製品: TMCO3 Mouse Monoclonal Antibody
カタログ: BF8751
タンパク質の説明: Mouse monoclonal antibody to TMCO3
アプリケーション: WB
反応性: Human
予測: Mouse, Rat
分子量: 70kD; 76kD(Calculated).
ユニプロット: Q6UWJ1

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製品説明

ソース:
Mouse
アプリケーション:
WB 1:500-1:3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human
クローナリティ:
Monoclonal [AFfirm8751]
特異性:
TMCO3 Mouse Monoclonal Antibody detects endogenous levels of TMCO3.
コンジュゲート:
Unconjugated.
精製:
Affinity-chromatography.
保存:
Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

C13orf11; Chromosome 13 open reading frame 11; Putative LAG1 interacting protein; Putative LAG1-interacting protein; Tmco3; TMCO3_HUMAN; Transmembrane and coiled coil domains 3; Transmembrane and coiled-coil domain-containing protein 3;

免疫原

免疫原:

A synthesized peptide derived from human TMCO3.

Uniprot:
遺伝子(ID):
発現特異性:
Q6UWJ1 TMCO3_HUMAN:

Expressed in the cornea, lens capsule and choroid-retinal pigment epithelium (at protein level).

タンパク質配列:
MKVLGRSFFWVLFPVLPWAVQAVEHEEVAQRVIKLHRGRGVAAMQSRQWVRDSCRKLSGLLRQKNAVLNKLKTAIGAVEKDVGLSDEEKLFQVHTFEIFQKELNESENSVFQAVYGLQRALQGDYKDVVNMKESSRQRLEALREAAIKEETEYMELLAAEKHQVEALKNMQHQNQSLSMLDEILEDVRKAADRLEEEIEEHAFDDNKSVKGVNFEAVLRVEEEEANSKQNITKREVEDDLGLSMLIDSQNNQYILTKPRDSTIPRADHHFIKDIVTIGMLSLPCGWLCTAIGLPTMFGYIICGVLLGPSGLNSIKSIVQVETLGEFGVFFTLFLVGLEFSPEKLRKVWKISLQGPCYMTLLMIAFGLLWGHLLRIKPTQSVFISTCLSLSSTPLVSRFLMGSARGDKEGDIDYSTVLLGMLVTQDVQLGLFMAVMPTLIQAGASASSSIVVEVLRILVLIGQILFSLAAVFLLCLVIKKYLIGPYYRKLHMESKGNKEILILGISAFIFLMLTVTELLDVSMELGCFLAGALVSSQGPVVTEEIATSIEPIRDFLAIVFFASIGLHVFPTFVAYELTVLVFLTLSVVVMKFLLAALVLSLILPRSSQYIKWIVSAGLAQVSEFSFVLGSRARRAGVISREVYLLILSVTTLSLLLAPVLWRAAITRCVPRPERRSSL

研究背景

機能:

Probable Na(+)/H(+) antiporter.

細胞の位置付け:

Membrane>Multi-pass membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Expressed in the cornea, lens capsule and choroid-retinal pigment epithelium (at protein level).

タンパク質ファミリー:

Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.

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