製品: ALG6 Mouse Monoclonal Antibody
カタログ: BF8754
タンパク質の説明: Mouse monoclonal antibody to ALG6
アプリケーション: WB
反応性: Human
予測: Mouse, Rat
分子量: 58kD(Calculated).
ユニプロット: Q9Y672

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製品説明

ソース:
Mouse
アプリケーション:
WB 1:500-1:3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human
クローナリティ:
Monoclonal [AFfirm8754]
特異性:
ALG6 Mouse Monoclonal Antibody detects endogenous levels of ALG6.
コンジュゲート:
Unconjugated.
精製:
Affinity-chromatography.
保存:
Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

Asparagine linked glycosylation 6; Asparagine linked glycosylation 6 homolog (S. cerevisiae alpha 1 3 glucosyltransferase); Asparagine linked glycosylation 6 homolog; Dolichyl P Glc:Man9GlcNAc2 PP dolichyl glucosyltransferase; Dolichyl P Glc:Man9GlcNAc2 PP dolichylglucosyltransferase; Dolichyl pyrophosphate Man9GlcNAc2 alpha 1 3 glucosyltransferase; E230028F23Rik; Man(9)GlcNAc(2) PP Dol alpha 1 3 glucosyltransferase; MGC124652; My 046; My046; OTTMUSP00000008309; RP23-35D18.4;

免疫原

免疫原:

A synthesized peptide derived from human ALG6.

Uniprot:
遺伝子(ID):
タンパク質配列:
MEKWYLMTVVVLIGLTVRWTVSLNSYSGAGKPPMFGDYEAQRHWQEITFNLPVKQWYFNSSDNNLQYWGLDYPPLTAYHSLLCAYVAKFINPDWIALHTSRGYESQAHKLFMRTTVLIADLLIYIPAVVLYCCCLKEISTKKKIANALCILLYPGLILIDYGHFQYNSVSLGFALWGVLGISCDCDLLGSLAFCLAINYKQMELYHALPFFCFLLGKCFKKGLKGKGFVLLVKLACIVVASFVLCWLPFFTEREQTLQVLRRLFPVDRGLFEDKVANIWCSFNVFLKIKDILPRHIQLIMSFCSTFLSLLPACIKLILQPSSKGFKFTLVSCALSFFLFSFQVHEKSILLVSLPVCLVLSEIPFMSTWFLLVSTFSMLPLLLKDELLMPSVVTTMAFFIACVTSFSIFEKTSEEELQLKSFSISVRKYLPCFTFLSRIIQYLFLISVITMVLLTLMTVTLDPPQKLPDLFSVLVCFVSCLNFLFFLVYFNIIIMWDSKSGRNQKKIS

研究背景

機能:

Adds the first glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Man(9)GlcNAc(2)-PP-Dol.

細胞の位置付け:

Endoplasmic reticulum membrane>Multi-pass membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
タンパク質ファミリー:

Belongs to the ALG6/ALG8 glucosyltransferase family.

研究領域

· Metabolism > Glycan biosynthesis and metabolism > N-Glycan biosynthesis.

· Metabolism > Global and overview maps > Metabolic pathways.

Restrictive clause

 

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