AFfirm™ ELAC1 Mouse Monoclonal Antibody - #BF8755

製品: ELAC1 Mouse Monoclonal Antibody
カタログ: BF8755
タンパク質の説明: Mouse monoclonal antibody to ELAC1
アプリケーション: WB
反応性: Human
予測: Mouse
分子量: 40-50kD; 40kD(Calculated).
ユニプロット: Q9H777

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関連ダウンロード
MS Report
HPLC Report
MSDS
説明書
COA
プロトコル
WB Handbook
IHC Protocol
IF/ICC Protocol

製品説明

ソース:
Mouse
アプリケーション:
WB 1:500-1:3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human
クローナリティ:
Monoclonal [AFfirm8755]
特異性:
ELAC1 Mouse Monoclonal Antibody detects endogenous levels of ELAC1.
コンジュゲート:
Unconjugated.
精製:
Affinity-chromatography.
保存:
Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ／展開

D29; Deleted in Ma29; ELAC 1; ElaC homolog 1 (E. coli); ElaC homolog 1; ElaC homolog protein 1; ELAC1; Ribonuclease Z 1; RNase Z 1; RNZ1_HUMAN; tRNA 3 endonuclease 1; tRNA 3' processing endoribonuclease; tRNA Z (short form); tRNA Z; tRNase Z 1; tRNase ZS; Zinc phosphodiesterase ELAC protein 1;

免疫原

免疫原:

A synthesized peptide derived from human ELAC1.

Uniprot:

Q9H777(RNZ1_HUMAN) >>Visit HPA database.

遺伝子(ID):
ELAC1(55520)
発現特異性:
Q9H777 RNZ1_HUMAN:

Widely expressed. Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.

タンパク質配列:
MSMDVTFLGTGAAYPSPTRGASAVVLRCEGECWLFDCGEGTQTQLMKSQLKAGRITKIFITHLHGDHFFGLPGLLCTISLQSGSMVSKQPIEIYGPVGLRDFIWRTMELSHTELVFHYVVHELVPTADQCPAEELKEFAHVNRADSPPKEEQGRTILLDSEENSYLLFDDEQFVVKAFRLFHRIPSFGFSVVEKKRPGKLNAQKLKDLGVPPGPAYGKLKNGISVVLENGVTISPQDVLKKPIVGRKICILGDCSGVVGDGGVKLCFEADLLIHEATLDDAQMDKAKEHGHSTPQMAATFAKLCRAKRLVLTHFSQRYKPVALAREGETDGIAELKKQAESVLDLQEVTLAEDFMVISIPIKK

研究背景

機能:

Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.

細胞の位置付け:

Cytoplasm>Cytosol. Nucleus.
Note: Mainly cytosolic.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Widely expressed. Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.

サブユニット構造:

Homodimer.

タンパク質ファミリー:

Belongs to the RNase Z family.

研究領域

· Genetic Information Processing > Translation > RNA transport.

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