AFfirm™ FAAH2 Mouse Monoclonal Antibody - #BF8792

製品: FAAH2 Mouse Monoclonal Antibody
カタログ: BF8792
タンパク質の説明: Mouse monoclonal antibody to FAAH2
アプリケーション: WB
反応性: Human
予測: Human
分子量: 60kD; 58kD(Calculated).
ユニプロット: Q6GMR7

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MS Report
HPLC Report
MSDS
説明書
COA
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WB Handbook
IHC Protocol
IF/ICC Protocol

製品説明

ソース:
Mouse
アプリケーション:
WB 1:500-1:3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human
クローナリティ:
Monoclonal [AFfirm8792]
特異性:
FAAH2 Mouse Monoclonal Antibody detects endogenous levels of FAAH2.
コンジュゲート:
Unconjugated.
精製:
Affinity-chromatography.
保存:
Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ／展開

AMDD; amidase domain containing; amidase domain containing protein; Amidase domain-containing protein; Anandamide amidohydrolase 2; FAAH-2; FAAH2; FAAH2_HUMAN; fatty acid amide hydrolase 2; Fatty-acid amide hydrolase 2; FLJ31204; Oleamide hydrolase 2; RP11-479E16; RP11-479E16.1;

免疫原

免疫原:

A synthesized peptide derived from human FAAH2.

Uniprot:

Q6GMR7(FAAH2_HUMAN) >>Visit HPA database.

遺伝子(ID):
FAAH2(158584)
発現特異性:
Q6GMR7 FAAH2_HUMAN:

Highly expressed in the brain, small intestine and testis. Also expressed in the heart, kidney, liver, lung and prostate.

タンパク質配列:
MAPSFTARIQLFLLRALGFLIGLVGRAALVLGGPKFASKTPRPVTEPLLLLSGMQLAKLIRQRKVKCIDVVQAYINRIKDVNPMINGIVKYRFEEAMKEAHAVDQKLAEKQEDEATLENKWPFLGVPLTVKEAFQLQGMPNSSGLMNRRDAIAKTDATVVALLKGAGAIPLGITNCSELCMWYESSNKIYGRSNNPYDLQHIVGGSSGGEGCTLAAACSVIGVGSDIGGSIRMPAFFNGIFGHKPSPGVVPNKGQFPLAVGAQELFLCTGPMCRYAEDLAPMLKVMAGPGIKRLKLDTKVHLKDLKFYWMEHDGGSFLMSKVDQDLIMTQKKVVVHLETILGASVQHVKLKKMKYSFQLWIAMMSAKGHDGKEPVKFVDLLGDHGKHVSPLWELIKWCLGLSVYTIPSIGLALLEEKLRYSNEKYQKFKAVEESLRKELVDMLGDDGVFLYPSHPTVAPKHHVPLTRPFNFAYTGVFSALGLPVTQCPLGLNAKGLPLGIQVVAGPFNDHLTLAVAQYLEKTFGGWVCPGKF

研究背景

機能:

Degrades bioactive fatty acid amides like oleamide, the endogenous cannabinoid, anandamide and myristic amide to their corresponding acids, thereby serving to terminate the signaling functions of these molecules. Hydrolyzes monounsaturated substrate anandamide preferentially as compared to polyunsaturated substrates.

細胞の位置付け:

Membrane>Single-pass membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Highly expressed in the brain, small intestine and testis. Also expressed in the heart, kidney, liver, lung and prostate.

サブユニット構造:

Homodimer.

タンパク質ファミリー:

Belongs to the amidase family.

Restrictive clause

 

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