AFfirm™ KCNAB3 Mouse Monoclonal Antibody - #BF8802

製品: KCNAB3 Mouse Monoclonal Antibody
カタログ: BF8802
タンパク質の説明: Mouse monoclonal antibody to KCNAB3
アプリケーション: WB
反応性: Human
予測: Mouse
分子量: 44kD(Calculated).
ユニプロット: O43448

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MS Report
HPLC Report
MSDS
説明書
COA
プロトコル
WB Handbook
IHC Protocol
IF/ICC Protocol

製品説明

ソース:
Mouse
アプリケーション:
WB 1:500-1:3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human
クローナリティ:
Monoclonal [AFfirm8802]
特異性:
KCNAB3 Mouse Monoclonal Antibody detects endogenous levels of KCNAB3.
コンジュゲート:
Unconjugated.
精製:
Affinity-chromatography.
保存:
Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ／展開

AKR6A9; K; K(+) channel subunit beta-3; K+ channel beta 3 subunit; KCAB3_HUMAN; KCNA3.1B; KCNA3B; KCNAB 3; Kcnab3; KV BETA 3; KV BETA3; Kv-beta-3; MGC116886; Voltage gated potassium channel subunit beta 3; Voltage-gated potassium channel subunit beta-3;

免疫原

免疫原:

A synthesized peptide derived from human KCNAB3.

Uniprot:

O43448(KCAB3_HUMAN) >>Visit HPA database.

遺伝子(ID):
KCNAB3(9196)
発現特異性:
O43448 KCAB3_HUMAN:

Brain specific. Most prominent expression in cerebellum. Weaker signals detected in cortex, occipital lobe, frontal lobe and temporal lobe. Not detected in spinal cord, heart, lung, liver, kidney, pancreas, placenta and skeletal muscle.

タンパク質配列:
MQVSIACTEQNLRSRSSEDRLCGPRPGPGGGNGGPAGGGHGNPPGGGGSGPKARAALVPRPPAPAGALRESTGRGTGMKYRNLGKSGLRVSCLGLGTWVTFGSQISDETAEDVLTVAYEHGVNLFDTAEVYAAGKAERTLGNILKSKGWRRSSYVITTKIFWGGQAETERGLSRKHIIEGLRGSLERLQLGYVDIVFANRSDPNCPMEEIVRAMTYVINQGLALYWGTSRWGAAEIMEAYSMARQFNLIPPVCEQAEHHLFQREKVEMQLPELYHKIGVGSVTWYPLACGLITSKYDGRVPDTCRASIKGYQWLKDKVQSEDGKKQQAKVMDLLPVAHQLGCTVAQLAIAWCLRSEGVSSVLLGVSSAEQLIEHLGALQVLSQLTPQTVMEIDGLLGNKPHSKK

研究背景

機能:

Accessory potassium channel protein which modulates the activity of the pore-forming alpha subunit. Alters the functional properties of Kv1.5.

細胞の位置付け:

Cytoplasm.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Brain specific. Most prominent expression in cerebellum. Weaker signals detected in cortex, occipital lobe, frontal lobe and temporal lobe. Not detected in spinal cord, heart, lung, liver, kidney, pancreas, placenta and skeletal muscle.

サブユニット構造:

Forms heteromultimeric complex with alpha subunits.

タンパク質ファミリー:

Alteration of functional properties of alpha subunit is mediated through N-terminal domain of beta subunit.

Belongs to the shaker potassium channel beta subunit family.

Restrictive clause

 

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