製品: UBTD1 Mouse Monoclonal Antibody
カタログ: BF8806
タンパク質の説明: Mouse monoclonal antibody to UBTD1
アプリケーション: WB
反応性: Human
予測: Mouse, Rat
分子量: 26kD(Calculated).
ユニプロット: Q9HAC8

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製品説明

ソース:
Mouse
アプリケーション:
WB 1:500-1:3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human
クローナリティ:
Monoclonal [AFfirm8806]
特異性:
UBTD1 Mouse Monoclonal Antibody detects endogenous levels of UBTD1.
コンジュゲート:
Unconjugated.
精製:
Affinity-chromatography.
保存:
Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

FLJ11807; Ubiquitin domain containing 1; Ubiquitin domain containing protein 1; Ubiquitin domain-containing protein 1; UBTD 1; UBTD1; UBTD1_HUMAN;

免疫原

免疫原:

A synthesized peptide derived from human UBTD1.

Uniprot:
遺伝子(ID):
タンパク質配列:
MGNCVGRQRRERPAAPGHPRKRAGRNEPLKKERLKWKSDYPMTDGQLRSKRDEFWDTAPAFEGRKEIWDALKAAAYAAEANDHELAQAILDGASITLPHGTLCECYDELGNRYQLPIYCLSPPVNLLLEHTEEESLEPPEPPPSVRREFPLKVRLSTGKDVRLSASLPDTVGQLKRQLHAQEGIEPSWQRWFFSGKLLTDRTRLQETKIQKDFVIQVIINQPPPPQD

研究背景

機能:

May be involved in the regulation of cellular senescence through a positive feedback loop with TP53. Is a TP53 downstream target gene that increases the stability of TP53 protein by promoting the ubiquitination and degradation of MDM2.

サブユニット構造:

Interacts with UBTD1.

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