AFfirm™ DMRT2 Mouse Monoclonal Antibody - #BF8815

製品: DMRT2 Mouse Monoclonal Antibody
カタログ: BF8815
タンパク質の説明: Mouse monoclonal antibody to DMRT2
アプリケーション: WB
反応性: Human
予測: Mouse, Rat
分子量: 60,70kD; 62kD(Calculated).
ユニプロット: Q9Y5R5

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関連ダウンロード
MS Report
HPLC Report
MSDS
説明書
COA
プロトコル
WB Handbook
IHC Protocol
IF/ICC Protocol

製品説明

ソース:
Mouse
アプリケーション:
WB 1:500-1:3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human
クローナリティ:
Monoclonal [AFfirm8815]
特異性:
DMRT2 Mouse Monoclonal Antibody detects endogenous levels of DMRT2.
コンジュゲート:
Unconjugated.
精製:
Affinity-chromatography.
保存:
Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ／展開

DMRT2; DMRT2_HUMAN; Doublesex and mab 3 related transcription factor 2; Doublesex- and mab-3-related transcription factor 2; Doublesex-like 2 protein; DSXL 2; DSXL-2; DSXL2; terra like protein;

免疫原

免疫原:

A synthesized peptide derived from human DMRT2.

Uniprot:

Q9Y5R5(DMRT2_HUMAN) >>Visit HPA database.

遺伝子(ID):
DMRT2(10655)
発現特異性:
Q9Y5R5 DMRT2_HUMAN:

Expressed in testis, kidney and skeletal muscle.

タンパク質配列:
MADPQAGSAAGDWEIDVESLELEEDVCGAPRSTPPGPSPPPADGDCEDDEDDDGVDEDAEEEGDGEEAGASPGMPGQPEQRGGPQPRPPLAPQASPAGTGPRERCTPAGGGAEPRKLSRTPKCARCRNHGVVSCLKGHKRFCRWRDCQCANCLLVVERQRVMAAQVALRRQQATEDKKGLSGKQNNFERKAVYQRQVRAPSLLAKSILEGYRPIPAETYVGGTFPLPPPVSDRMRKRRAFADKELENIMLEREYKEREMLETSQAAALFLPNRMVPGPDYNSYKSAYSPSPVEPPSKDFCNFLPTCLDLTMQYSGSGNMELISSNVSVATTYRQYPLSSRFLVWPKCGPISDTLLYQQCLLNATTSVQALKPGASWDLKGARVQDGLSAEQDMMPSKLEGSLVLPHTPEIQTTRSDLQGHQAVPERSAFSPPRRNFSPIVDTDSLAAQGHVLTKISKENTRHPLPLRHNPFHSLFQQTLTDKSGPELKTPFVKEAFEETPKKHRECLVKDNQKYTFTIDRCAKDLFVAKQVGTKLSVNEPLSFSVESILKRPSSAITRVSQ

研究背景

機能:

Transcriptional activator that directly regulates early activation of the myogenic determination gene MYF5 by binding in a sequence-specific manner to the early epaxial enhancer element of it. Involved in somitogenesis during embryogenesis and somite development and differentiation into sclerotome and dermomyotome. Required for the initiation and/or maintenance of proper organization of the sclerotome, dermomyotome and myotome (By similarity).

細胞の位置付け:

Nucleus.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Expressed in testis, kidney and skeletal muscle.

サブユニット構造:

Homodimer.

タンパク質ファミリー:

Belongs to the DMRT family.

Restrictive clause

 

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