Cyclophilin B Mouse Monoclonal Antibody - #BF8825
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
折りたたみ／展開
AA408962; AA553318; AI844835; Cphn 2; Cphn2; Cyclophilin B; Cyclophilin like protein; CyP 20b; CYP S1; CYP-S1; CYPB; EC 5.2.1.8; MGC14109; MGC2224; OI9; peptidyl prolyl cis trans isomerase B; Peptidyl prolyl cis trans isomerase B precursor; Peptidyl-prolyl cis-trans isomerase B; peptidylprolyl isomerase B (cyclophilin B); Peptidylprolyl isomerase B; PPIase; PPIase B; Ppib; PPIB_HUMAN; Rotamase; Rotamase B; S cyclophilin; S-cyclophilin; SCYLP;
免疫原
- P23284 PPIB_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MLRLSERNMKVLLAAALIAGSVFFLLLPGPSAADEKKKGPKVTVKVYFDLRIGDEDVGRVIFGLFGKTVPKTVDNFVALATGEKGFGYKNSKFHRVIKDFMIQGGDFTRGDGTGGKSIYGERFPDENFKLKHYGPGWVSMANAGKDTNGSQFFITTVKTAWLDGKHVVFGKVLEGMEVVRKVESTKTDSRDKPLKDVIIADCGKIEVEKPFAIAKE
PTMs - P23284 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| Y47 | Phosphorylation | Uniprot | |
| R51 | Methylation | Uniprot | |
| K67 | Ubiquitination | Uniprot | |
| T72 | Phosphorylation | Uniprot | |
| T81 | Phosphorylation | Uniprot | |
| K84 | Ubiquitination | Uniprot | |
| Y88 | Phosphorylation | Uniprot | |
| K98 | Acetylation | Uniprot | |
| K98 | Ubiquitination | Uniprot | |
| R109 | Methylation | Uniprot | |
| K116 | Ubiquitination | Uniprot | |
| R122 | Methylation | Uniprot | |
| K129 | Methylation | Uniprot | |
| K129 | Ubiquitination | Uniprot | |
| K131 | Acetylation | Uniprot | |
| K131 | Ubiquitination | Uniprot | |
| S139 | Phosphorylation | Uniprot | |
| T147 | Phosphorylation | Uniprot | |
| S150 | Phosphorylation | Uniprot | |
| K158 | Ubiquitination | Uniprot | |
| K165 | Acetylation | Uniprot | |
| K165 | Ubiquitination | Uniprot | |
| K171 | Acetylation | Uniprot | |
| S184 | Phosphorylation | Uniprot | |
| T185 | Phosphorylation | Uniprot | |
| T187 | Phosphorylation | Uniprot | |
| S189 | Phosphorylation | Uniprot | |
| C202 | S-Nitrosylation | Uniprot | |
| K209 | Acetylation | Uniprot | |
| K209 | Ubiquitination | Uniprot | |
| K215 | Acetylation | Uniprot |
研究背景
PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding.
Endoplasmic reticulum lumen. Melanosome.
Note: Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:17081065).
Interacts with DYM. Interacts with CALR, CLGN and CANX.
Belongs to the cyclophilin-type PPIase family. PPIase B subfamily.
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