AFfirm™ Annexin VII Mouse Monoclonal Antibody - #BF8827
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
折りたたみ／展開
Annexin A7; Annexin VII; Annexin-7; ANX7; ANXA7; ANXA7_HUMAN; SNX; Synexin;
免疫原
Isoform 1 is expressed in brain, heart and skeletal muscle. Isoform 2 is more abundant in liver, lung, kidney, spleen, fibroblasts and placenta.
- P20073 ANXA7_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSYPGYPPTGYPPFPGYPPAGQESSFPPSGQYPYPSGFPPMGGGAYPQVPSSGYPGAGGYPAPGGYPAPGGYPGAPQPGGAPSYPGVPPGQGFGVPPGGAGFSGYPQPPSQSYGGGPAQVPLPGGFPGGQMPSQYPGGQPTYPSQINTDSFSSYPVFSPVSLDYSSEPATVTQVTQGTIRPAANFDAIRDAEILRKAMKGFGTDEQAIVDVVANRSNDQRQKIKAAFKTSYGKDLIKDLKSELSGNMEELILALFMPPTYYDAWSLRKAMQGAGTQERVLIEILCTRTNQEIREIVRCYQSEFGRDLEKDIRSDTSGHFERLLVSMCQGNRDENQSINHQMAQEDAQRLYQAGEGRLGTDESCFNMILATRSFPQLRATMEAYSRMANRDLLSSVSREFSGYVESGLKTILQCALNRPAFFAERLYYAMKGAGTDDSTLVRIVVTRSEIDLVQIKQMFAQMYQKTLGTMIAGDTSGDYRRLLLAIVGQ
PTMs - P20073 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K196 | Acetylation | Uniprot | |
| K199 | Ubiquitination | Uniprot | |
| S216 | Phosphorylation | Uniprot | |
| K224 | Ubiquitination | Uniprot | |
| K228 | Ubiquitination | Uniprot | |
| K233 | Acetylation | Uniprot | |
| K233 | Ubiquitination | Uniprot | |
| K237 | Ubiquitination | Uniprot | |
| K268 | Ubiquitination | Uniprot | |
| T275 | Phosphorylation | Uniprot | |
| T286 | Phosphorylation | Uniprot | |
| C298 | S-Nitrosylation | Uniprot | |
| K309 | Ubiquitination | Uniprot | |
| S400 | Phosphorylation | Uniprot | |
| Y402 | Phosphorylation | Uniprot | |
| Y426 | Phosphorylation | Uniprot | |
| Y427 | Phosphorylation | Uniprot | |
| K430 | Acetylation | Uniprot | |
| K430 | Ubiquitination | Uniprot | |
| S447 | Phosphorylation | Uniprot | |
| K455 | Ubiquitination | Uniprot | |
| S475 | Phosphorylation | Uniprot | |
| Y478 | Phosphorylation | Uniprot |
研究背景
Calcium/phospholipid-binding protein which promotes membrane fusion and is involved in exocytosis.
Isoform 1 is expressed in brain, heart and skeletal muscle. Isoform 2 is more abundant in liver, lung, kidney, spleen, fibroblasts and placenta.
Interacts with PDCD6.
A pair of annexin repeats may form one binding site for calcium and phospholipid.
Belongs to the annexin family.
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