AFfirm™ ARHGAP42 Mouse Monoclonal Antibody - #BF8862
製品説明
ソース:
Mouse
アプリケーション:
WB 1:500-1:3000
*The optimal dilutions should be determined by the end user.
*Tips:
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
反応性:
Human
クローナリティ:
Monoclonal [AFfirm8862]
特異性:
ARHGAP42 Mouse Monoclonal Antibody detects endogenous levels of total ARHGAP42.
コンジュゲート:
Unconjugated.
精製:
Affinity-chromatography.
保存:
Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:
折りたたみ／展開
ARHGAP42; FLJ32810; GRAF3; RHG42_HUMAN; Rho GTPase-activating protein 10-like; Rho GTPase-activating protein 42; Rho-type GTPase-activating protein 42;
免疫原
免疫原:
Uniprot:
遺伝子(ID):
発現特異性:
タンパク質配列:
- A6NI28 RHG42_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MGLPTLEFSDSYLDSPDFRERLQCHEIELERTNKFIKELIKDGSLLIGALRNLSMAVQKFSQSLQDFQFECIGDAETDDEISIAQSLKEFARLLIAVEEERRRLIQNANDVLIAPLEKFRKEQIGAAKDGKKKFDKESEKYYSILEKHLNLSAKKKESHLQEADTQIDREHQNFYEASLEYVFKIQEVQEKKKFEFVEPLLSFLQGLFTFYHEGYELAQEFAPYKQQLQFNLQNTRNNFESTRQEVERLMQRMKSANQDYRPPSQWTMEGYLYVQEKRPLGFTWIKHYCTYDKGSKTFTMSVSEMKSSGKMNGLVTSSPEMFKLKSCIRRKTDSIDKRFCFDIEVVERHGIITLQAFSEANRKLWLEAMDGKEPIYTLPAIISKKEEMYLNEAGFNFVRKCIQAVETRGITILGLYRIGGVNSKVQKLMNTTFSPKSPPDIDIDIELWDNKTITSGLKNYLRCLAEPLMTYKLHKDFIIAVKSDDQNYRVEAVHALVHKLPEKNREMLDILIKHLVKVSLHSQQNLMTVSNLGVIFGPTLMRAQEETVAAMMNIKFQNIVVEILIEHYEKIFHTAPDPSIPLPQPQSRSGSRRTRAICLSTGSRKPRGRYTPCLAEPDSDSYSSSPDSTPMGSIESLSSHSSEQNSTTKSASCQPREKSGGIPWIATPSSSNGQKSLGLWTTSPESSSREDATKTDAESDCQSVASVTSPGDVSPPIDLVKKEPYGLSGLKRASASSLRSISAAEGNKSYSGSIQSLTSVGSKETPKASPNPDLPPKMCRRLRLDTASSNGYQRPGSVVAAKAQLFENVGSPKPVSSGRQAKAMYSCKAEHSHELSFPQGAIFSNVYPSVEPGWLKATYEGKTGLVPENYVVFL
PTMs - A6NI28 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| T32 | Phosphorylation | Uniprot | |
| K128 | Acetylation | Uniprot | |
| K131 | Acetylation | Uniprot | |
| Y142 | Phosphorylation | Uniprot | |
| K154 | Ubiquitination | Uniprot | |
| T332 | Phosphorylation | Uniprot | |
| Y376 | Phosphorylation | Uniprot | |
| T377 | Phosphorylation | Uniprot | |
| K424 | Ubiquitination | Uniprot | |
| S587 | Phosphorylation | Uniprot | |
| S638 | Phosphorylation | Uniprot | |
| S641 | Phosphorylation | Uniprot | |
| S683 | Phosphorylation | Uniprot | |
| S728 | Phosphorylation | Uniprot | |
| K731 | Methylation | Uniprot | |
| S734 | Phosphorylation | Uniprot | |
| S740 | Phosphorylation | Uniprot | |
| S742 | Phosphorylation | Uniprot | |
| S749 | Phosphorylation | Uniprot | |
| S751 | Phosphorylation | Uniprot | |
| S753 | Phosphorylation | Uniprot | |
| S769 | Phosphorylation | Uniprot | |
| T786 | Phosphorylation | Uniprot | |
| S788 | Phosphorylation | Uniprot | |
| S789 | Phosphorylation | Uniprot | |
| Y792 | Phosphorylation | Uniprot | |
| S797 | Phosphorylation | Uniprot | |
| S811 | Phosphorylation | Uniprot | |
| T858 | Phosphorylation | Uniprot | |
| Y870 | Phosphorylation | Uniprot |
研究背景
機能:
May influence blood pressure by functioning as a GTPase-activating protein for RHOA in vascular smooth muscle.
組織特異性:
Highly and selectively expressed in smooth muscle cells.
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