AFfirm™ Scavenger Receptor BII Mouse Monoclonal Antibody - #BF8913

製品: Scavenger Receptor BII Mouse Monoclonal Antibody
カタログ: BF8913
タンパク質の説明: Mouse monoclonal antibody to Scavenger Receptor BII
アプリケーション: WB
反応性: Human
予測: Mouse, Rat
分子量: 60~80kD; 54kD(Calculated).
ユニプロット: Q14108

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関連ダウンロード
MS Report
HPLC Report
MSDS
説明書
COA
プロトコル
WB Handbook
IHC Protocol
IF/ICC Protocol

製品説明

ソース:
Mouse
アプリケーション:
WB 1:500-1:3000
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human
クローナリティ:
Monoclonal [AFfirm8913]
特異性:
Scavenger Receptor BII Mouse Monoclonal Antibody detects endogenous levels of total Scavenger Receptor BII.
コンジュゲート:
Unconjugated.
精製:
Affinity-chromatography.
保存:
Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ／展開

85 kDa lysosomal membrane sialoglycoprotein; 85 kDa lysosomal sialoglycoprotein scavenger receptor class B member 2; AMRF; CD36; CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 2 (lysosomal integral membrane protein II); CD36 antigen; CD36 antigen-like 2; CD36L2; EPM4; HLGP85; LGP85; LIMP 2; LIMP II; LIMP2; LIMPII; Lysosomal integral membrane protein II; Lysosome membrane protein 2; Lysosome membrane protein II; OTTHUMP00000160590; OTTHUMP00000219176; Scarb2; Scavenger receptor class B member 2; Scavenger receptor class B, member 2; SCRB2_HUMAN; SR BII; SRBII;

免疫原

免疫原:

A synthesized peptide derived from Human Scavenger Receptor BII.

Uniprot:

Q14108(SCRB2_HUMAN) >>Visit HPA database.

遺伝子(ID):
SCARB2(950)
タンパク質配列:
MGRCCFYTAGTLSLLLLVTSVTLLVARVFQKAVDQSIEKKIVLRNGTEAFDSWEKPPLPVYTQFYFFNVTNPEEILRGETPRVEEVGPYTYRELRNKANIQFGDNGTTISAVSNKAYVFERDQSVGDPKIDLIRTLNIPVLTVIEWSQVHFLREIIEAMLKAYQQKLFVTHTVDELLWGYKDEILSLIHVFRPDISPYFGLFYEKNGTNDGDYVFLTGEDSYLNFTKIVEWNGKTSLDWWITDKCNMINGTDGDSFHPLITKDEVLYVFPSDFCRSVYITFSDYESVQGLPAFRYKVPAEILANTSDNAGFCIPEGNCLGSGVLNVSICKNGAPIIMSFPHFYQADERFVSAIEGMHPNQEDHETFVDINPLTGIILKAAKRFQINIYVKKLDDFVETGDIRTMVFPVMYLNESVHIDKETASRLKSMINTTLIITNIPYIIMALGVFFGLVFTWLACKGQGSMDEGTADERAPLIRT

研究背景

機能:

Acts as a lysosomal receptor for glucosylceramidase (GBA) targeting.

(Microbial infection) Acts as a receptor for enterovirus 71.

細胞の位置付け:

Lysosome membrane>Multi-pass membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
サブユニット構造:

Interacts with GBA.

(Microbial infection) Interacts with enterovirus 71 capsid proteins VP1 and VP2.

タンパク質ファミリー:

Belongs to the CD36 family.

研究領域

· Cellular Processes > Transport and catabolism > Lysosome.   (View pathway)

Restrictive clause

 

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For Research Use Only.
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